Copper Histidine

Base Information

Chemical Name:Copper Histidine
CAS No.:12561-67-0
Deprecated CAS:12275-37-5,12281-85-5,3685-42-5,5610-61-7,49871-83-2
Molecular Formula:C₁₂H₁₆CuN₆O₄
Molecular Weight:371.843
Hs Code.:
UNII:9078K3MO9U
DSSTox Substance ID:DTXSID30154803
Nikkaji Number:J1.412.545K
Wikidata:Q27271298
Mol file:12561-67-0.mol

Synonyms:copper bis(histidinate);copper bis(histidinate), (L,trans)-isomer;copper bis(histidinate), N,O(D)-isomer;copper bis(histidinate), N,O(L)-isomer;copper bishistidinate;Cu(His)2

Suppliers and Price of Copper Histidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Copper Histidine

Chemical Property:

Vapor Pressure:3.25E-09mmHg at 25°C
Boiling Point:458.9°C at 760 mmHg
Flash Point:231.3°C
PSA：189.66000
LogP:-2.54310
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:371.052900
Heavy Atom Count:23
Complexity:145

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(NC=N1)CC(C(=O)[O-])N.C1=C(NC=N1)CC(C(=O)[O-])N.[Cu+2]
Isomeric SMILES:C1=C(NC=N1)C[C@@H](C(=O)[O-])N.C1=C(NC=N1)C[C@@H](C(=O)[O-])N.[Cu+2]
Recent ClinicalTrials:Copper Histidinate Treatment for Menkes Disease

Technology Process of Copper Histidine

There total 2 articles about Copper Histidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: copper(II) perchlorate hexahydrate

: 71-00-1
D,L-histidine

: 32218-09-0,51466-44-5,956498-52-5,13870-80-9,1175619-51-8,16884-54-1,313692-55-6,764598-10-9,85129-24-4,33847-28-8,956498-50-3,12561-67-0,741240-83-5,780754-19-0,23859-16-7,33847-27-7,785775-41-9,33847-33-5
Cu(H₂NCH(CO₂)CH₂C₃H₃N₂)2

Guidance literature:: With sodium hydroxide; In water; Cu salt and histidine (molar ratio 1:5) dissolved in water; shaken for 1h; pH adjusted to 7.3 (NaOH);
DOI:10.1021/ic049699q

Reference yield:

: 5934-29-2
U-[13C,15N]-histidine hydrochloride hydrate

: copper(II) chloride monohydrate

: 1175619-51-8,12561-67-0,1357926-85-2,1357926-95-4,13870-80-9,1411976-55-0,16884-54-1,23859-16-7,313692-55-6,32218-09-0,33847-27-7,33847-28-8,33847-33-5,51466-44-5,741240-83-5,764598-10-9,780754-19-0,785775-41-9,85129-24-4,956498-50-3,956498-52-5
Cu(OCOCH(NH₂)CH₂(C₃H₃N₂))2

: Cu(OCOCH(NH₂)CH₂(C₃H₃N₂))2

Guidance literature:: With sodium hydroxide; water; In water; aq. soln. of ligand and CuCl2, NaOH, pH 7.23, room temp.; not isolated; detected by Raman spectroscopy;
DOI:10.1246/bcsj.53.3131