6-O-Methyl-D-galactose

Base Information

• Chemical Name: 6-O-Methyl-D-galactose
• CAS No.: 6779-91-5
• Molecular Formula: C7H14O6
• Molecular Weight: 194.185
• Hs Code.: 2912499000
• UNII: 8PWX2M67NE
• Nikkaji Number: J92.785F
• Wikidata: Q27270865
• Mol file: 6779-91-5.mol

Synonyms:6-O-Methyl-D-galactose;6-O-Methylgalactose;6-Methylgalactose;Galactose, 6-O-methyl-;D-Galactose, 6-O-methyl-;8PWX2M67NE;Galactose, 6-O-methyl-, D-;UNII-8PWX2M67NE;SCHEMBL565806;GFHNQKKLOLZRQE-WNJXEPBRSA-N;Q27270865

Chemical Property of 6-O-Methyl-D-galactose

Chemical Property:

• Vapor Pressure: 7.49E-07mmHg at 25°C
• Refractive Index: 1.564
• Boiling Point: 366.3°C at 760 mmHg
• Flash Point: 175.3°C
• PSA: 107.22000
• Density: 1.5g/cm³
• LogP: -2.72470
• XLogP3: -2.9
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 194.07903816
• Heavy Atom Count: 13
• Complexity: 150

Purity/Quality:

97% ^*data from raw suppliers

6-O-Methyl-D-galactopyranose ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCC(C(C(C(C=O)O)O)O)O
• Isomeric SMILES: COC[C@H]([C@@H]([C@@H]([C@H](C=O)O)O)O)O

Technology Process of 6-O-Methyl-D-galactose

There total 13 articles about 6-O-Methyl-D-galactose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

3,5-O-benzylidene-1,2-O-isopropylidene-6-O-methyl-α-D-glucofuranose (18930-13-7) → 6-O-methyl-D-glucose (6779-91-5,51844-37-2,70932-59-1,98243-48-2,2461-70-3,53472-75-6)

Guidance literature:

With sulfuric acid;

Reference yield:

→ 6-O-methyl-D-glucose (6779-91-5,51844-37-2,70932-59-1,98243-48-2,2461-70-3,53472-75-6)

Guidance literature:

With ethanol; palladium; Hydrogenation;

DOI:10.1021/ja01571a064

Reference yield:

1,2:5,6-di-O-isopropylidene-α-D-glucofuranose (582-52-5) → 6-O-methyl-D-glucose (6779-91-5,51844-37-2,70932-59-1,98243-48-2,2461-70-3,53472-75-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 96.4 percent / aq. tetrafluoro boric acid / acetone; H₂O / 5 h / 20 °C

2: 51 percent / pyridine / 48 h / 0 - 5 °C

tetrafluoroboric acid; In pyridine; water; acetone;

DOI:10.1016/0008-6215(85)85167-3

upstream raw materials:

3,5-O-benzylidene-1,2-O-isopropylidene-6-O-methyl-α-D-glucofuranose

1,2-O-isopropylidene-α-D-glucofuranose 6-p-nitrobenzoate

3,5-O-benzylidene-1,2-O-isopropylidene-α-D-glucofuranoside

1,2-O-isopropylidene-α-D-glucofuranose

Downstream raw materials:

(4-nitro-phenyl)-(O²,O³,O⁴-triacetyl-O⁶-methyl-β-D-glucopyranoside)

p-nitrophenyl 6-O-methyl-α-D-glucopyranoside

O⁴-methyl-D-[2]tetrosulose-bis-phenylhydrazone

O¹,O²,O³,O⁴-Tetrabenzoyl-O⁶-methyl-α-D-glucopyranose