2'-ETHYLPROPIOPHENONE

Base Information

• Chemical Name: 2'-ETHYLPROPIOPHENONE
• CAS No.: 16819-79-7
• Molecular Formula: C11H14 O
• Molecular Weight: 162.232
• Mol file: 16819-79-7.mol

Synonyms:Propiophenone,2'-ethyl- (8CI)

Chemical Property of 2'-ETHYLPROPIOPHENONE

Chemical Property:

• Boiling Point: 250.2±19.0 °C(Predicted)
• Flash Point: 99oC
• PSA: 17.07000
• Density: 0.98
• LogP: 2.91540

Purity/Quality:

97% ^*data from raw suppliers

2'-Ethylpropiophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2'-ETHYLPROPIOPHENONE

There total 6 articles about 2'-ETHYLPROPIOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1-(2-ethylphenyl)propanol (67541-89-3) → 1-(2-ethylphenyl)propan-1-one (16819-79-7)

Guidance literature:

With trifluoroacetic anhydride; In dichloromethane; dimethyl sulfoxide; at -30 ℃; for 3h; Reagent/catalyst;

Reference yield: 70.0%

Et2Mg*LiCl + o-chlorobenzoyl chloride (609-65-4) → 1-(2-ethylphenyl)propan-1-one (16819-79-7)

Guidance literature:

With manganese(II) chloride tetrahydrate; In tetrahydrofuran; at -30 ℃; for 0.5h; Inert atmosphere;

DOI:10.1002/aoc.1567

Reference yield:

(7S,8S)-7-Ethyl-8-methyl-bicyclo[4.2.0]octa-1(6),2,4-trien-7-ol → 2-phenylpentan-3-one (63801-22-9,103130-61-6,103130-62-7,16819-77-5) + 1-(2-ethylphenyl)propan-1-one (16819-79-7)

Guidance literature:

With sodium methylate; In methanol; Yield given. Yields of byproduct given; Heating;

DOI:10.1002/hlca.19980810207

upstream raw materials:

fluorobenzene

pentan-3-one

bromobenzene

o-chlorobenzoyl chloride

Downstream raw materials:

1-(2-ethylphenyl)propanol

2-bromo-1-(2-ethylphenyl)propan-1-one

eperisone hydrochloride