Eperisone hydrochloride

Base Information

Chemical Name:Eperisone hydrochloride
CAS No.:56839-43-1
Molecular Formula:C17H26ClNO
Molecular Weight:295.853
Hs Code.:
UNII:U38O8U7P6X
DSSTox Substance ID:DTXSID8047844
Wikidata:Q27889924
NCI Thesaurus Code:C83693
ChEMBL ID:CHEMBL2360601
Mol file:56839-43-1.mol

Synonyms:(4'-ethyl-2-methyl-3-piperidino)propiophenone;4-EMPP;E-0646;eperisone

Suppliers and Price of Eperisone hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
EperisoneHydrochloride
1g
$ 95.00

Crysdot
Eperisonehydrochloride 97%
100g
$ 563.00

Chemenu
Eperisonehydrochloride 97%
100g
$ 532.00

American Custom Chemicals Corporation
EPERISONE HYDROCHLORIDE 95.00%
1G
$ 135.45

AK Scientific
EperisoneHCl
25g
$ 225.00

AK Scientific
EperisoneHCl
100mg
$ 95.00

AHH
Eperisonehydrochloride 98%
0.5g
$ 230.00

Total 107 raw suppliers

Chemical Property of Eperisone hydrochloride

Chemical Property:

Appearance/Colour:White solid
Vapor Pressure:3.46E-06mmHg at 25°C
Melting Point:169-171°C
Boiling Point:386.8 °C at 760 mmHg
Flash Point:137.4 °C
PSA：20.31000
Density:0.994g/cm³
LogP:4.29360
Storage Temp.:-20°C Freezer
Solubility.:Methanol (Slightly), Water (Slightly)
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:295.1702921
Heavy Atom Count:20
Complexity:275

Purity/Quality:

99% ^*data from raw suppliers

EperisoneHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CC=C(C=C1)C(=O)C(C)CN2CCCCC2.Cl
Recent ClinicalTrials:Phase 3 Study to Evaluate the Efficacy and Safety of DW-1030 and Eperisone HCl in Acute Back Pain Patients
Recent EU Clinical Trials:Efficacia e Sicurezza di Eperisone Cloridrato
Description Eperisone hydrochloride is a centrally acting muscle relaxant useful in the management of various spastic conditions including cervical spondylosis and cerebral palsy. It is structurally related to tolperisone.
Uses A spasmolytic agent related structurally to Tolperisone (T535475). Muscle relaxant (skeletal). Used as antispasmodic
Therapeutic Function Muscle relaxant

Technology Process of Eperisone hydrochloride

There total 3 articles about Eperisone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 646-06-0
1,3-DIOXOLANE

: 27465-51-6
1-(4-ethylphenyl)-1-propanone

: 6091-44-7
piperidine hydrochloride

: 56839-43-1
eperisone hydrochloride

Guidance literature:: With hydrogenchloride; at 90 ℃; for 6.5h;
DOI:10.1248/cpb.42.1676

Reference yield: 67.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 16819-79-7
1-(2-ethylphenyl)propan-1-one

: 6091-44-7
piperidine hydrochloride

: 56839-43-1
eperisone hydrochloride

Guidance literature:: In isopropyl alcohol; at 90 - 100 ℃; for 5h;

Reference yield:

: 1973-22-4
1-bromo-2-ethylbenzene

: 56839-43-1
eperisone hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: magnesium; iodine / tetrahydrofuran / 2 h / -5 - 5 °C

1.2: 20 °C

2.1: trifluoroacetic anhydride / dimethyl sulfoxide; dichloromethane / 3 h / -30 °C

3.1: isopropyl alcohol / 5 h / 90 - 100 °C

With iodine; magnesium; trifluoroacetic anhydride; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide; isopropyl alcohol;