2-(Isocyanomethyl)pyridine

Base Information

• Chemical Name: 2-(Isocyanomethyl)pyridine
• CAS No.: 60148-13-2
• Molecular Formula: C7H6N2
• Molecular Weight: 118.138
• DSSTox Substance ID: DTXSID60377967
• Wikidata: Q72485277
• Mol file: 60148-13-2.mol

Synonyms:2-(isocyanomethyl)pyridine;60148-13-2;2-isocyanomethylpridine;2-isocyanomethylpyridine;2-PyridylMethyl isocyanide;SCHEMBL12194161;DTXSID60377967;MFCD02664553;AKOS006280262;AS-19823;FT-0651371;EN300-1836683;J-506442

Chemical Property of 2-(Isocyanomethyl)pyridine

Chemical Property:

• XLogP3: 0.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 118.053098200
• Heavy Atom Count: 9
• Complexity: 122

Purity/Quality:

98%min ^*data from raw suppliers

2-(isocyanomethyl)pyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: [C-]#[N+]CC1=CC=CC=N1
• Uses: 2-(isocyanomethyl)pyridine acts as a reagent in the synthesis of azaindolizines with two nitrogen atoms in a 5-membered ring.

Technology Process of 2-(Isocyanomethyl)pyridine

There total 1 articles about 2-(Isocyanomethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

2-(Aminomethyl)pyridine (3731-51-9) + chloroform (67-66-3,8013-54-5) → imidazo[1,5-a]pyridine (274-47-5) + (2-Pyridylmethyl)isonitrile (60148-13-2)

Guidance literature:

With sodium hydroxide; tetra-n-propylammonium bromide; In 1,2-dimethoxyethane; at 50 ℃; for 4.5h; Product distribution;

DOI:10.1021/jo00007a028

upstream raw materials:

2-(Aminomethyl)pyridine

chloroform

Refernces