7-Tertbutyl-2-nitrofluorene

Base Information

Chemical Name:7-Tertbutyl-2-nitrofluorene
CAS No.:60758-15-8
Molecular Formula:C₁₇H₁₇NO₂
Molecular Weight:267.327
Hs Code.:2904209090
DSSTox Substance ID:DTXSID70483942
Nikkaji Number:J1.158.683J
Wikidata:Q82321822
Mol file:60758-15-8.mol

Synonyms:7-TERTBUTYL-2-NITROFLUORENE;60758-15-8;DTXSID70483942

Suppliers and Price of 7-Tertbutyl-2-nitrofluorene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 7-Tertbutyl-2-nitrofluorene

Chemical Property:

PSA：45.82000
LogP:4.98670
XLogP3:5.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:267.125928785
Heavy Atom Count:20
Complexity:381

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC2=C(C=C1)C3=C(C2)C=C(C=C3)[N+](=O)[O-]

Technology Process of 7-Tertbutyl-2-nitrofluorene

There total 7 articles about 7-Tertbutyl-2-nitrofluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 243122-80-7
2-(4-tert-Butylphenyl)-5-nitrobenzyl alcohol

: 60758-15-8
7-tert-Butyl-2-nitrofluorene

Guidance literature:: With methanesulfonic acid; In chloroform; Heating;
DOI:10.1055/s-1999-3537

Reference yield: 30.0%

: 58775-05-6
2,7-di-tert-butyl-9H-fluorene

: 60758-15-8
7-tert-Butyl-2-nitrofluorene

: 91611-99-3
2,7-di-t-butyl-4-nitrofluorene

Guidance literature:: With nitric acid; acetic acid; In acetic anhydride; at -20 - 0 ℃; for 2h;
DOI:10.1055/s-1984-30835

Reference yield:

: 6942-36-5
methyl 2-bromo-5-nitrobenzoate

: 60758-15-8
7-tert-Butyl-2-nitrofluorene

Guidance literature:: Multi-step reaction with 3 steps

1.1: t-BuLi / diethyl ether; pentane / 1 h / -78 °C

1.2: ZnCl₂ / tetrahydrofuran / 1 h

1.3: 73 percent / Pd(dba)2; dppf / tetrahydrofuran / 18 h / 20 °C

2.1: 99 percent / LiBH₄ / diethyl ether; methanol; tetrahydrofuran / 0 - 20 °C

3.1: 72 percent / PPA; MeSO₃H / CHCl₃ / Heating

With lithium borohydride; methanesulfonic acid; tert.-butyl lithium; In tetrahydrofuran; methanol; diethyl ether; chloroform; pentane; 1.1: Metallation / 1.2: Transmetallation / 1.3: Negishi coupling / 2.1: Reduction / 3.1: Cyclization;
DOI:10.1055/s-1999-3537