2,5-dioxo-1-Pyrrolidineacetaldehyde

Base Information

Chemical Name:2,5-dioxo-1-Pyrrolidineacetaldehyde
CAS No.:676558-37-5
Molecular Formula:C₆H₇NO₃
Molecular Weight:141.126
Hs Code.:
European Community (EC) Number:810-676-6
Mol file:676558-37-5.mol

Synonyms:676558-37-5;1-Pyrrolidineacetaldehyde,2,5-dioxo-(9CI);2,5-dioxo-1-Pyrrolidineacetaldehyde;1-Pyrrolidineacetaldehyde, 2,5-dioxo-;SCHEMBL2559072;AKOS011069508;2-(2,5-dioxopyrrolidin-1-yl)acetaldehyde

Suppliers and Price of 2,5-dioxo-1-Pyrrolidineacetaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
2,5-dioxo-1-Pyrrolidineacetaldehyde
25G
$ 1290.00

AccelPharmtech
2,5-dioxo-1-Pyrrolidineacetaldehyde
5G
$ 440.00

AccelPharmtech
2,5-dioxo-1-Pyrrolidineacetaldehyde
1G
$ 230.00

Total 3 raw suppliers

Chemical Property of 2,5-dioxo-1-Pyrrolidineacetaldehyde

Chemical Property:

Boiling Point:337.7±25.0 °C(Predicted)
PKA:-1.70±0.20(Predicted)
PSA：54.45000
Density:1.310±0.06 g/cm3(Predicted)
LogP:-0.72780
XLogP3:-1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:141.042593085
Heavy Atom Count:10
Complexity:171

Purity/Quality:

98% ^*data from raw suppliers

2,5-dioxo-1-Pyrrolidineacetaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1=O)CC=O

Technology Process of 2,5-dioxo-1-Pyrrolidineacetaldehyde

There total 1 articles about 2,5-dioxo-1-Pyrrolidineacetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 18190-44-8
1-(2-Hydroxy-ethyl)-pyrrolidine-2,5-dione

: 676558-37-5
2-succinimidoethanal

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 20 ℃;
DOI:10.1016/j.tetasy.2003.12.011

Reference yield:

: 17176-77-1
Dibenzyl phosphite

: 676558-37-5
2-succinimidoethanal

: dibenzyl (2-(2,5-dioxopyrrolidin-1-yl)-1-hydroxyethyl)phosphonate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1021/acs.jmedchem.6b01644

Reference yield:

: 676558-37-5
2-succinimidoethanal

: 2'-((3S)-2-((1S)-phenylethylamino)-2-azabicyclo-[2.2.1]-hept-5-ene-3-ylmethyl)-pyrrolidine-1',3'-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 4 Angstroem molecular sieves / CH₂Cl₂

2: BF₃*Et₂O; trifluoroacetic acid / CH₂Cl₂ / -78 - 20 °C

With 4 A molecular sieve; boron trifluoride diethyl etherate; trifluoroacetic acid; In dichloromethane; 2: aza-Diels-Alder reaction;
DOI:10.1016/j.tetasy.2003.12.011