1H-Pyrrolo[3,2-c]pyridine,1,2-dimethyl-

Base Information

• Chemical Name: 1H-Pyrrolo[3,2-c]pyridine,1,2-dimethyl-
• CAS No.: 680859-99-8
• Molecular Formula: C9H10N2
• Molecular Weight: 146.1891
• Hs Code.: 2933990090
• Mol file: 680859-99-8.mol

Synonyms:1H-Pyrrolo[3,2-c]pyridine,1,2-dimethyl-;1H-Pyrrolo[3,2-c]pyridine,1,2-dimethyl-(9CI)

Chemical Property of 1H-Pyrrolo[3,2-c]pyridine,1,2-dimethyl-

Chemical Property:

• Boiling Point: 263.7±20.0 °C(Predicted)
• PKA: 9.77±0.40(Predicted)
• PSA: 17.82000
• Density: 1.09±0.1 g/cm3(Predicted)
• LogP: 1.88170
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Pyrrolo[3,2-c]pyridine,1,2-dimethyl-

There total 2 articles about 1H-Pyrrolo[3,2-c]pyridine,1,2-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

Allyl acetate (591-87-7) + (3-iodopyridin-4-yl)methylamine (680859-97-6) → 1,2-dimethyl-1H-pyrrolo[3,2-c]pyridine (680859-99-8)

Guidance literature:

With potassium carbonate; lithium chloride; palladium diacetate; In N,N-dimethyl-formamide; at 120 ℃; for 20h;

DOI:10.3987/com-03-9965

Reference yield: 33.0%

N-(3-pyridylmethylidene)tert-butylamine (56752-28-4) → 3-pyridinecarboxaldehyde (500-22-1) + pyridine-3-carbonitrile (100-54-9,121697-66-3,1232169-17-3,68271-95-4) + 7-methyl-[1,6]naphthyridine (99839-11-9) + 3-methyl-[2,7]naphthyridine (108994-74-7) + 6-methyl-[1,7]naphthyridine (1260841-18-6) + 1,2-dimethylpyrrolo<2,3-b>pyridine (113975-38-5) + 3-methyl-[1,8]naphthyridine (14759-22-9) + 3-methyl-[2,6]naphthyridine (35968-89-9) + 1,2-dimethyl-1H-pyrrolo[3,2-c]pyridine (680859-99-8)

Guidance literature:

at 800 ℃; under 7.50075E-05 Torr;

DOI:10.1002/ejoc.201400112

upstream raw materials:

Allyl acetate

(3-iodopyridin-4-yl)methylamine

N-(3-pyridylmethylidene)tert-butylamine