5-Methoxy-7-methyl-1H-indole

Base Information

Chemical Name:5-Methoxy-7-methyl-1H-indole
CAS No.:61019-05-4
Molecular Formula:C10H11NO
Molecular Weight:161.203
Hs Code.:2933990090
European Community (EC) Number:894-438-7
DSSTox Substance ID:DTXSID80491730
Wikidata:Q82336638
Mol file:61019-05-4.mol

Synonyms:5-Methoxy-7-methyl-1H-indole;61019-05-4;5-Methoxy-7-methylindole;MFCD09027022;1H-Indole, 5-methoxy-7-methyl-;5-methoxy7-methyl-1H-indole;SCHEMBL5372057;AMY9787;DTXSID80491730;YGPVRHHGKCQSIL-UHFFFAOYSA-N;AKOS006290557;PB43145;AS-49425;SY112801;CS-0114970;FT-0738110;I10193;A868833

Suppliers and Price of 5-Methoxy-7-methyl-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-methoxy-7-methyl-1H-indole
50mg
$ 45.00

Matrix Scientific
5-Methoxy-7-methylindole
25g
$ 3938.00

Matrix Scientific
5-Methoxy-7-methylindole
1g
$ 104.00

Matrix Scientific
5-Methoxy-7-methylindole
5g
$ 312.00

Crysdot
5-Methoxy-7-methyl-1H-indole 95+%
1g
$ 196.00

Crysdot
5-Methoxy-7-methyl-1H-indole 95+%
5g
$ 587.00

Crysdot
5-Methoxy-7-methyl-1H-indole 95+%
10g
$ 980.00

Chemenu
5-methoxy-7-methyl-1H-indole 95%+
1000g
$ 16560.00

Alichem
5-Methoxy-7-methyl-1H-indole
5g
$ 413.40

Alichem
5-Methoxy-7-methyl-1H-indole
10g
$ 707.20

Total 33 raw suppliers

Chemical Property of 5-Methoxy-7-methyl-1H-indole

Chemical Property:

Melting Point:65-66 °C
Boiling Point:309.74 °C at 760 mmHg
PKA:17.00±0.30(Predicted)
Flash Point:113.573 °C
PSA：25.02000
Density:1.134 g/cm³
LogP:2.48490
Storage Temp.:Sealed in dry,Room Temperature
Water Solubility.:Slightly soluble in water.
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:161.084063974
Heavy Atom Count:12
Complexity:160

Purity/Quality:

99%, ^*data from raw suppliers

5-methoxy-7-methyl-1H-indole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC2=C1NC=C2)OC
Uses 5-Methoxy-7-methylindole is employed as a intermediate for chemical research and pharmaceutical.

Technology Process of 5-Methoxy-7-methyl-1H-indole

There total 4 articles about 5-Methoxy-7-methyl-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.5%

: 74798-63-3
1-(2-amino-5-methoxy-3-methylphenyl)-2-chloroethanone

: 61019-05-4
5-methoxy-7-methyl-1H-indole

Guidance literature:: With sodium tetrahydroborate; In 1,4-dioxane; water; at 120 ℃; for 1h;

Reference yield: 78.8%

: C₁₄H₁₄N₂O₃

: 61019-05-4
5-methoxy-7-methyl-1H-indole

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In ethanol; for 48h; Reflux; Industrial scale;

Reference yield:

: 102-50-1
2-methyl-4-methoxyaniline

: 61019-05-4
5-methoxy-7-methyl-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) BCl₃, TiCl₄, 2.) 2 N HCl / 1.) C₆H₆, CH₂Cl₂, reflux, 3 h, 2.) C₆H₆, CH₂Cl₂, 80 deg C, 45 min

2: 86 percent / NaBH₄ / dioxane; H₂O / 1 h / Heating

With hydrogenchloride; sodium tetrahydroborate; boron trichloride; titanium tetrachloride; In 1,4-dioxane; water;
DOI:10.1021/jm00185a014