2-(5-VINYL-1-AZABICYCLO[2,2,2]OCTAN-2-YL)INDOLE

Base Information

Chemical Name:2-(5-VINYL-1-AZABICYCLO[2,2,2]OCTAN-2-YL)INDOLE
CAS No.:61119-84-4
Molecular Formula:C17H20N2
Molecular Weight:252.359
Hs Code.:2933990090
Mol file:61119-84-4.mol

Synonyms:2-(5-VINYL-1-AZABICYCLO[2,2,2]OCTAN-2-YL)INDOLE

Suppliers and Price of 2-(5-VINYL-1-AZABICYCLO[2,2,2]OCTAN-2-YL)INDOLE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(5-VINYL-1-AZABICYCLO[2,2,2]OCTAN-2-YL)INDOLE 95.00%
5MG
$ 497.33

Total 3 raw suppliers

Chemical Property of 2-(5-VINYL-1-AZABICYCLO[2,2,2]OCTAN-2-YL)INDOLE

Chemical Property:

PSA：19.03000
LogP:3.67470

Purity/Quality:

99% ^*data from raw suppliers

2-(5-VINYL-1-AZABICYCLO[2,2,2]OCTAN-2-YL)INDOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(5-VINYL-1-AZABICYCLO[2,2,2]OCTAN-2-YL)INDOLE

There total 2 articles about 2-(5-VINYL-1-AZABICYCLO[2,2,2]OCTAN-2-YL)INDOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 95-53-4
o-toluidine

: 61119-84-4
(1S,2S,4S,5R)-2-(1H-Indol-2-yl)-5-vinyl-1-aza-bicyclo[2.2.2]octane

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / LiI, cyclohexene oxide / chlorotrimethylsilane / neat (no solvent) / 20 h / Heating

2: 1.) n-BuLi / 1.) hexane, 0 deg C, reflux, 6.5 h; 2.) THF, from -78 deg C up to room temp.

With n-butyllithium; cyclohexane-1,2-epoxide; lithium iodide; chloro-trimethyl-silane; In neat (no solvent);
DOI:10.1016/S0040-4020(01)90586-1

Reference yield:

: 66140-88-3
ethyl-5-vinyl-2-quinuclidine carboxylate

: 82185-43-1
N-(trimethylsilyl)-o-toluidine

: 61119-84-4
(1S,2S,4S,5R)-2-(1H-Indol-2-yl)-5-vinyl-1-aza-bicyclo[2.2.2]octane

Guidance literature:: With n-butyllithium; Yield given. Multistep reaction; 1.) hexane, 0 deg C, reflux, 6.5 h; 2.) THF, from -78 deg C up to room temp.;
DOI:10.1016/S0040-4020(01)90586-1

Reference yield:

: 75-21-8,99932-75-9
oxirane

: 61119-84-4
(1S,2S,4S,5R)-2-(1H-Indol-2-yl)-5-vinyl-1-aza-bicyclo[2.2.2]octane

: 482-28-0
(+)-cinchonamine

Guidance literature:: With methyl magnesium iodide; Yield given. Multistep reaction; 1.) diethyl ether, room temp. 15 min; 2.) diethyl ether, room temp. 1 h,reflux, 2 h;
DOI:10.1016/S0040-4020(01)90586-1