5,7-Dimethoxy-2-methyl-2,3-dihydro-1H-inden-1-one

Base Information

Chemical Name:5,7-Dimethoxy-2-methyl-2,3-dihydro-1H-inden-1-one
CAS No.:61227-52-9
Molecular Formula:C12H14O3
Molecular Weight:206.23776
Hs Code.:2914509090
DSSTox Substance ID:DTXSID30457240
Nikkaji Number:J460.211K
Pharos Ligand ID:4J8VHZULR4R2
ChEMBL ID:CHEMBL152826
Mol file:61227-52-9.mol

Synonyms:5,7-Dimethoxy-2-methyl-2,3-dihydro-1H-inden-1-one;61227-52-9;5,7-dimethoxy-2-methyl-2,3-dihydroinden-1-one;CHEMBL152826;SCHEMBL12059598;DTXSID30457240;BDBM50008549;AKOS015964095;AC-18672;A868781;2,3-Dihydro-5,7-dimethoxy-2-methyl-1H-inden-1-one;N-(4-CHLOROBENZHYDRYL)-NORBORNANAMINEHYDROCHLORIDE

Suppliers and Price of 5,7-Dimethoxy-2-methyl-2,3-dihydro-1H-inden-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5,7-Dimethoxy-2-methyl-2,3-dihydro-1H-inden-1-one 95+%
1g
$ 772.00

Crysdot
5,7-Dimethoxy-2-methyl-2,3-dihydro-1H-inden-1-one 95+%
250mg
$ 309.00

American Custom Chemicals Corporation
5,7-DIMETHOXY-2-METHYL-INDAN-1-ONE 95.00%
5MG
$ 499.79

Alichem
5,7-Dimethoxy-2-methyl-2,3-dihydro-1H-inden-1-one
250mg
$ 535.30

Total 8 raw suppliers

Chemical Property of 5,7-Dimethoxy-2-methyl-2,3-dihydro-1H-inden-1-one

Chemical Property:

Vapor Pressure:3.39E-05mmHg at 25°C
Refractive Index:1.53
Boiling Point:354.2°C at 760 mmHg
Flash Point:159.3°C
PSA：35.53000
Density:1.126g/cm³
LogP:2.07870
Storage Temp.:2-8°C
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:206.094294304
Heavy Atom Count:15
Complexity:251

Purity/Quality:

97% ^*data from raw suppliers

5,7-Dimethoxy-2-methyl-2,3-dihydro-1H-inden-1-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC2=C(C1=O)C(=CC(=C2)OC)OC

Technology Process of 5,7-Dimethoxy-2-methyl-2,3-dihydro-1H-inden-1-one

There total 6 articles about 5,7-Dimethoxy-2-methyl-2,3-dihydro-1H-inden-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 122333-94-2
3-(3,5-dimethoxyphenyl)-2-methylpropanoic acid

: 61227-52-9
5,7-dimethoxy-2-methylindan-1-one

Guidance literature:: With PPA; Polyphosphoric acid (PPA); at 90 ℃; for 0.2h;
DOI:10.1021/jo00278a043

Reference yield: 80.0%

: 618085-52-2
5-(3,5-dimethoxybenzyl)-2,2,5-trimethyl-1,3-dioxane-4,6-dione

: 61227-52-9
5,7-dimethoxy-2-methylindan-1-one

Guidance literature:: scandium tris(trifluoromethanesulfonate); In nitromethane; for 0.75h; Heating;
DOI:10.1021/ol035817m

Reference yield:

: 7311-34-4
3,5-dimethoxybenzaldehdye

: 61227-52-9
5,7-dimethoxy-2-methylindan-1-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: piperidinium acetate / ethanol / 0.5 h

1.2: 61 percent / NaBH₃CN / ethanol / 0 - 20 °C

2.1: 79 percent / K₂CO₃ / dimethylformamide

3.1: 80 percent / Sc(OTf)3 / nitromethane / 0.75 h / 100 °C

With piperdinium acetate; potassium carbonate; scandium tris(trifluoromethanesulfonate); In nitromethane; ethanol; N,N-dimethyl-formamide; 3.1: Friedel-Crafts acylation;
DOI:10.1021/jo0483724