Technology Process of Benzeneacetic acid, alpha-cyano-4-ethyl-, ethyl ester (9CI)
There total 1 articles about Benzeneacetic acid, alpha-cyano-4-ethyl-, ethyl ester (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium tert-butylate;
bis-triphenylphosphine-palladium(II) chloride;
Multistep reaction;
1.) 1,2-dimethoxyethane, room temperature, 10 min, 2.) 1,2-dimethoxyethane, 70 deg C, 8 h;
DOI:10.1246/bcsj.62.3896
- Guidance literature:
-
Multi-step reaction with 2 steps
1: concd. hydrochloric acid, calcium chloride / benzene / 1.) room temperature, 3 h, 2.) 55 deg C, 2 h, 3.) reflux, 5 h
2: 1.) LiAlH4, 2.) 5percent sodium hydroxide / 1.) diethyl ether, reflux, 6 h, 2.) ethyl acetate, room temperature, 10 h
With
hydrogenchloride; sodium hydroxide; lithium aluminium tetrahydride; calcium chloride;
In
benzene;
DOI:10.1246/bcsj.62.3896
- Guidance literature:
-
With
hydrogenchloride; calcium chloride;
In
benzene;
1.) room temperature, 3 h, 2.) 55 deg C, 2 h, 3.) reflux, 5 h;
DOI:10.1246/bcsj.62.3896