Benzyl [1-(tert-butylamino)-3-methyl-1-oxobutan-2-yl]carbamate

Base Information

Chemical Name:Benzyl [1-(tert-butylamino)-3-methyl-1-oxobutan-2-yl]carbamate
CAS No.:61274-17-7
Molecular Formula:C17H26N2O3
Molecular Weight:306.4
Hs Code.:2924299090
ChEMBL ID:CHEMBL338515
DSSTox Substance ID:DTXSID30558029
Mol file:61274-17-7.mol

Synonyms:61274-17-7;Benzyl [1-(tert-butylamino)-3-methyl-1-oxobutan-2-yl]carbamate;benzyl N-[1-(tert-butylamino)-3-methyl-1-oxobutan-2-yl]carbamate;CHEMBL338515;SCHEMBL18822181;DTXSID30558029

Suppliers and Price of Benzyl [1-(tert-butylamino)-3-methyl-1-oxobutan-2-yl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BENZYL-1-(TERT-BUTYLAMINO)-3-METHYL-1-OXOBUTAN-2-YL CARBAMATE 98.00%
100G
$ 3465.00

American Custom Chemicals Corporation
BENZYL-1-(TERT-BUTYLAMINO)-3-METHYL-1-OXOBUTAN-2-YL CARBAMATE 98.00%
5G
$ 1970.43

Total 7 raw suppliers

Chemical Property of Benzyl [1-(tert-butylamino)-3-methyl-1-oxobutan-2-yl]carbamate

Chemical Property:

Boiling Point:486.2 °C at 760 mmHg
PKA:11.15±0.46(Predicted)
Flash Point:247.8 °C
PSA：74.41000
Density:1.057g/cm³
LogP:3.89680
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:306.19434270
Heavy Atom Count:22
Complexity:369

Purity/Quality:

99% ^*data from raw suppliers

BENZYL-1-(TERT-BUTYLAMINO)-3-METHYL-1-OXOBUTAN-2-YL CARBAMATE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)NC(C)(C)C)NC(=O)OCC1=CC=CC=C1

Technology Process of Benzyl [1-(tert-butylamino)-3-methyl-1-oxobutan-2-yl]carbamate

There total 3 articles about Benzyl [1-(tert-butylamino)-3-methyl-1-oxobutan-2-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 75-64-9
tert-butylamine

: 61274-17-7
N-carbobenzoxy-L-valyl-tert-butylamide

Guidance literature:: With 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 16h; Inert atmosphere;
DOI:10.1039/c4cc03261f

Reference yield: 75.0%

: 3496-11-5
2,5-dioxopyrrolidin-1-yl (2S)-2-(((benzyloxy)carbonyl)amino)-3-methylbutanoate

: 75-64-9
tert-butylamine

: 61274-17-7
N-carbobenzoxy-L-valyl-tert-butylamide

Guidance literature:: In 1,4-dioxane; for 20h;
DOI:10.1007/BF00955289

Reference yield:

: 1149-26-4
(S)-N-(benzyloxycarbonyl)valine

: 61274-17-7
N-carbobenzoxy-L-valyl-tert-butylamide

Guidance literature:: Multi-step reaction with 2 steps

1: 58.5 percent / dicyclohexylcarbodiimide / dioxane; CH₂Cl₂ / 1.) 0 deg C, 3 h, 2.) 20 deg C, 24 h

2: 75 percent / dioxane / 20 h

With dicyclohexyl-carbodiimide; In 1,4-dioxane; dichloromethane;
DOI:10.1007/BF00955289