1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-

Base Information

Chemical Name:1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-
CAS No.:685514-01-6
Molecular Formula:C16H26N2OSi
Molecular Weight:290.481
Hs Code.:
Mol file:685514-01-6.mol

Synonyms:1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-

Suppliers and Price of 1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-5-ol
1g
$ 826.00

Crysdot
1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol 95+%
5g
$ 423.00

Crysdot
1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol 95+%
1g
$ 140.00

ChemScene
1H-Pyrrolo[2,3-b]pyridin-5-ol,1-[tris(1-methylethyl)silyl]-
1g
$ 112.00

ChemScene
1H-Pyrrolo[2,3-b]pyridin-5-ol,1-[tris(1-methylethyl)silyl]-
250mg
$ 56.00

ChemScene
1H-Pyrrolo[2,3-b]pyridin-5-ol,1-[tris(1-methylethyl)silyl]-
5g
$ 336.00

Chemenu
1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol 95%+
5g
$ 535.00

Chemenu
1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol 95%+
100mg
$ 53.00

Chemenu
1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol 95%+
1g
$ 166.00

Chemenu
1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridin-5-ol 95%+
250mg
$ 78.00

Total 25 raw suppliers

Chemical Property of 1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-

Chemical Property:

Vapor Pressure:4.03E-05mmHg at 25°C
Refractive Index:1.534
Boiling Point:341.6°C at 760 mmHg
PKA:8.50±0.40(Predicted)
Flash Point:160.4°C
PSA：38.05000
Density:1.03g/cm³
LogP:4.76550

Purity/Quality:

99%, ^*data from raw suppliers

1-Triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-5-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]-

There total 8 articles about 1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: C₁₆H₂₇BN₂O₂Si

: 685514-01-6
1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-ol

Guidance literature:: With dihydrogen peroxide; sodium hydroxide; In tetrahydrofuran; at 0 ℃; for 1h; Inert atmosphere;

Reference yield: 49.0%

: 685513-98-8
4-chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridin-5-ol

: 685514-01-6
1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-ol

Guidance literature:: With acetic acid; zinc; In ethyl acetate; at 20 ℃; for 18h;
DOI:10.1016/j.tetlet.2004.01.122

Reference yield:

: 55052-28-3
4-chloro-7-azaindole

: 685514-01-6
1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / tetrahydrofuran; hexane / 0.25 h / 0 °C

1.2: 93.5 percent / tetrahydrofuran; hexane / 18 h / 80 °C

2.1: sec-butyllithium / tetrahydrofuran; cyclohexane / 0.5 h / -78 °C

2.2: 65 percent / (R)-camphorsulfonyl oxaziridine / tetrahydrofuran; cyclohexane / 0.42 h / -78 °C

3.1: 49 percent / zinc; acetic acid / ethyl acetate / 18 h / 20 °C

With sec.-butyllithium; sodium hydride; acetic acid; zinc; In tetrahydrofuran; hexane; cyclohexane; ethyl acetate;
DOI:10.1016/j.tetlet.2004.01.122