6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE HYDROCHLORIDE

Base Information

• Chemical Name: 6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE HYDROCHLORIDE
• CAS No.: 623931-31-7
• Molecular Formula: C6H9ClN2OS
• Molecular Weight: 192.67
• Hs Code.: 2934999090
• Mol file: 623931-31-7.mol

Synonyms:6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE HYDROCHLORIDE;6,7-Dihydro-4H-pyran[4,3-d]thiazol-2-ylamine hydrochloride

Chemical Property of 6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE HYDROCHLORIDE

Chemical Property:

• PSA: 76.38000
• LogP: 2.18120
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

6,7-Dihydro-4H-pyrano[4,3-d]thiazol-2-amine hydrochloride Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE HYDROCHLORIDE

There total 3 articles about 6,7-DIHYDRO-4H-PYRANO[4,3-D]THIAZOL-2-YLAMINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

Tetrahydro-4H-pyran-4-one (29943-42-8,143562-54-3) + thiourea (17356-08-0) → 6,7-dihydro-4H-pyrano[4,3-d][1,3]thiazol-2-amine hydrochloride (623931-31-7)

Guidance literature:

Tetrahydro-4H-pyran-4-one; With sulfuryl dichloride; In tetrachloromethane; at 0 - 20 ℃; for 4h;

With water; at 0 ℃;

thiourea; In tetrahydrofuran; ethanol; for 8h; Heating / reflux;

Reference yield:

thiourea (17356-08-0) + 3-chlorodihydro-2H-pyran-4(3H)-one (160427-98-5) → 6,7-dihydro-4H-pyrano[4,3-d][1,3]thiazol-2-amine hydrochloride (623931-31-7)

Guidance literature:

In tetrahydrofuran; ethanol; for 8h; Heating;

DOI:10.1016/j.bmc.2007.11.006

Reference yield:

tetrahydropyran-4-enyl chloride (24265-21-2) + thiourea (17356-08-0) → 6,7-dihydro-4H-pyrano[4,3-d][1,3]thiazol-2-amine hydrochloride (623931-31-7)

Guidance literature:

In tetrahydrofuran; ethanol; for 8h; Heating / reflux;

upstream raw materials:

tetrahydropyran-4-enyl chloride

thiourea

3-chlorodihydro-2H-pyran-4(3H)-one

Tetrahydro-4H-pyran-4-one