4,5-DIBROMOTHIOPHENE-2-CARBOXYLIC ACID, 98+%

Base Information

• Chemical Name: 4,5-DIBROMOTHIOPHENE-2-CARBOXYLIC ACID, 98+%
• CAS No.: 7311-68-4
• Molecular Formula: C5H2Br2O2S
• Molecular Weight: 285.944
• Hs Code.: 2934999090
• Mol file: 7311-68-4.mol

Synonyms:4,5-Dibromo-thiophen-2-carboxylic acid;

Chemical Property of 4,5-DIBROMOTHIOPHENE-2-CARBOXYLIC ACID, 98+%

Chemical Property:

• Melting Point: 215-220°C
• Boiling Point: 350.015 °C at 760 mmHg
• PKA: 2.90±0.10(Predicted)
• Flash Point: 165.484 °C
• PSA: 65.54000
• Density: 2.309 g/cm³
• LogP: 2.97130
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

3,5-Dibromothiophene-2-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,5-DIBROMOTHIOPHENE-2-CARBOXYLIC ACID, 98+%

There total 8 articles about 4,5-DIBROMOTHIOPHENE-2-CARBOXYLIC ACID, 98+% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,5-dibromothiophen (3141-27-3) + carbon dioxide (124-38-9,18923-20-1) → 3,5-dibromothiophene-2-carboxylic acid (7311-68-4)

Guidance literature:

With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; 1.) -78 deg C, 15 min, 2.) -78 deg C -> 0 deg C;

Reference yield: 66.0%

2,3,5-tribromothiophene (3141-24-0) + carbon dioxide (124-38-9,18923-20-1) → 3,5-dibromothiophene-2-carboxylic acid (7311-68-4)

Guidance literature:

2,3,5-tribromothiophene; With n-butyllithium; In diethyl ether; hexane; at -78 ℃;

carbon dioxide; In diethyl ether; hexane; Further stages.;

DOI:10.1039/b612235c

Reference yield:

2,3,5-tribromothiophene (3141-24-0) → 3,5-dibromothiophene-2-carboxylic acid (7311-68-4) + 4,5-Dibromo-thiophene-2-carboxylic acid (6324-10-3)

Guidance literature:

With methyl bromide; diethyl ether; magnesium; Behandeln der Reaktionsloesung mit Kohlendioxid;

upstream raw materials:

2,4-dibromothiophene

n-butyllithium

diethyl ether

methylammonium carbonate

Downstream raw materials:

3,5-dibromo-thiophene-2-carbonyl chloride

ethyl 3,5-dibromothiophene-2-carboxylate

2-(hydroxymethyl)-3,5-dibromothiophene

3,5-dibromo-thiophene-2-carboxylic acid methyl ester