2-chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide

Base Information

Chemical Name:2-chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide
CAS No.:649701-41-7
Molecular Formula:C14H14 Cl N3 O
Molecular Weight:275.73
Hs Code.:2933199090
DSSTox Substance ID:DTXSID10380885
Wikidata:Q82171381
Mol file:649701-41-7.mol

Synonyms:649701-41-7;2-chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide;N1-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)-2-chloroacetamide;2-chloro-N-(5-cyclopropyl-2-phenylpyrazol-3-yl)acetamide;DTXSID10380885;MFCD00105029;AKOS001450375;UPCMLD0ENAT5988976:001;CS-0244937;FT-0729510;EN300-29695;Z285575588

Suppliers and Price of 2-chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N1-(3-CYCLOPROPYL-1-PHENYL-1H-PYRAZOL-5-YL)-2-CHLOROACETAMIDE 95.00%
1G
$ 462.00

American Custom Chemicals Corporation
N1-(3-CYCLOPROPYL-1-PHENYL-1H-PYRAZOL-5-YL)-2-CHLOROACETAMIDE 95.00%
2.5G
$ 1227.82

AK Scientific
2-Chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide
10g
$ 1678.00

AK Scientific
2-Chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide
2.5g
$ 819.00

AK Scientific
2-Chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide
500mg
$ 356.00

AK Scientific
2-Chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide
250mg
$ 235.00

Total 4 raw suppliers

Chemical Property of 2-chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide

Chemical Property:

PSA：46.92000
LogP:3.00000
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:275.0825398
Heavy Atom Count:19
Complexity:329

Purity/Quality:

95% ^*data from raw suppliers

N1-(3-CYCLOPROPYL-1-PHENYL-1H-PYRAZOL-5-YL)-2-CHLOROACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1C2=NN(C(=C2)NC(=O)CCl)C3=CC=CC=C3

Technology Process of 2-chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide

There total 1 articles about 2-chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 79-04-9
chloroacetyl chloride

: 175137-45-8
3-cyclopropyl-1-phenyl-1H-pyrazol-5-amine

: 649701-41-7
2-chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide

Guidance literature:: With triethylamine; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/jm5006429

Reference yield: 71.0%

: 649701-41-7
2-chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide

: 1614229-10-5
2-azido-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide

Guidance literature:: With sodium azide; In ethanol; at 60 ℃; for 16h;
DOI:10.1021/jm5006429

Reference yield:

: 649701-41-7
2-chloro-N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)acetamide

: 1614229-03-6
N-(3-cyclopropyl-1-phenyl-1H-pyrazol-5-yl)-2-(4-(4-(4-methyl-1H-imidazole-1-yl)phenyl)-1H-1,2,3-triazol-1-yl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium azide / ethanol / 16 h / 60 °C

2: copper(II) sulfate; copper / tert-butyl alcohol; water / 0.17 h / 125 °C / Microwave irradiation

With sodium azide; copper; copper(II) sulfate; In ethanol; water; tert-butyl alcohol;
DOI:10.1021/jm5006429