2-Oxazolidinone,5-(hydroxymethyl)-3-(2-propenyl)-(9CI)

Base Information

• Chemical Name: 2-Oxazolidinone,5-(hydroxymethyl)-3-(2-propenyl)-(9CI)
• CAS No.: 649761-78-4
• Molecular Formula: C₇H₁₁NO₃
• Molecular Weight: 157.169
• Mol file: 649761-78-4.mol

Synonyms:2-Oxazolidinone,5-(hydroxymethyl)-3-(2-propenyl)- (9CI);N-Allyl-5-hydroxymethyloxazolidin-2-one

Chemical Property of 2-Oxazolidinone,5-(hydroxymethyl)-3-(2-propenyl)-(9CI)

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

3-ALLYL-5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Oxazolidinone,5-(hydroxymethyl)-3-(2-propenyl)-(9CI)

There total 3 articles about 2-Oxazolidinone,5-(hydroxymethyl)-3-(2-propenyl)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

1-amino-2-propene (107-11-9,30551-89-4) + silver carbonate + 1,2-Epoxy-3-bromopropane (3132-64-7,82584-73-4) → N-allyl-5-hydroxymethyloxazolidin-2-one (649761-78-4)

Guidance literature:

With TEA; In methanol; Heating;

DOI:10.1021/jo0501644

Reference yield:

3-Allylamino-propane-1,2-diol (13348-89-5) + Diethyl carbonate (105-58-8,76619-83-5) → N-allyl-5-hydroxymethyloxazolidin-2-one (649761-78-4)

Guidance literature:

With sodium methylate; In methanol; at 110 ℃; for 12h;

DOI:10.1016/j.ijpharm.2013.11.048

Reference yield:

silver (II) carbonate + potassium carbonate (584-08-7) + 1-amino-2-propene (107-11-9,30551-89-4) + 1,2-Epoxy-3-bromopropane (3132-64-7,82584-73-4) → N-allyl-5-hydroxymethyloxazolidin-2-one (649761-78-4)

Guidance literature:

In methanol;

DOI:10.2174/15734064113096660043

upstream raw materials:

1-amino-2-propene

1,2-Epoxy-3-bromopropane

3-Allylamino-propane-1,2-diol

Diethyl carbonate

Downstream raw materials:

3-allyl-5-(4-benzhydryl-piperazin-1-ylmethyl)-oxazolidin-2-one