4-(Piperidin-4-ylcarbonyl)morpholine

Base Information

Chemical Name:4-(Piperidin-4-ylcarbonyl)morpholine
CAS No.:63214-57-3
Molecular Formula:C10H18N2O2
Molecular Weight:198.265
Hs Code.:2934999090
DSSTox Substance ID:DTXSID70979234
Wikidata:Q82964808

Synonyms:63214-57-3;4-(piperidin-4-ylcarbonyl)morpholine;morpholin-4-yl(piperidin-4-yl)methanone;Morpholino(piperidin-4-yl)methanone;4-(4-piperidinylcarbonyl)morpholine;4-(piperidine-4-carbonyl)morpholine;SCHEMBL493454;DTXSID70979234;MFCD03372501;STK500666;Morpholin-4-ylpiperidin-4-ylmethanone;AKOS000199736;4-[(piperidin-4-yl)carbonyl]morpholine;TS-02806;(Morpholin-4-yl)(piperidin-4-yl)methanone;BB 0220153;FT-0724595;EN300-34178;4-(4-Piperidinylcarbonyl)morpholine, AldrichCPR;MORPHOLIN-4-YL-PIPERIDIN-4-YL-METHANONEHYDROCHLORIDE

Suppliers and Price of 4-(Piperidin-4-ylcarbonyl)morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Piperidin-4-ylcarbonyl)morpholine
50mg
$ 175.00

Matrix Scientific
4-(Piperidin-4-ylcarbonyl)morpholine 97%
1g
$ 341.00

Crysdot
Morpholino(piperidin-4-yl)methanone 95+%
1g
$ 317.00

Atlantic Research Chemicals
4-(Piperidin-4-ylcarbonyl)morpholine 95%
1gm:
$ 123.71

American Custom Chemicals Corporation
4-(PIPERIDIN-4-YLCARBONYL)MORPHOLINE 95.00%
5G
$ 1168.42

American Custom Chemicals Corporation
4-(PIPERIDIN-4-YLCARBONYL)MORPHOLINE 95.00%
2.5G
$ 983.88

American Custom Chemicals Corporation
4-(PIPERIDIN-4-YLCARBONYL)MORPHOLINE 95.00%
1G
$ 721.57

AK Scientific
4-(Piperidin-4-ylcarbonyl)morpholine
1g
$ 510.00

Total 9 raw suppliers

Chemical Property of 4-(Piperidin-4-ylcarbonyl)morpholine

Chemical Property:

Vapor Pressure:1.16E-05mmHg at 25°C
Boiling Point:369.8°C at 760 mmHg
PKA:9.80±0.10(Predicted)
Flash Point:177.4°C
PSA：41.57000
Density:1.111±0.06 g/cm3(Predicted)
LogP:0.91350
XLogP3:-0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:198.136827821
Heavy Atom Count:14
Complexity:196

Purity/Quality:

99%, ^*data from raw suppliers

4-(Piperidin-4-ylcarbonyl)morpholine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1C(=O)N2CCOCC2

Technology Process of 4-(Piperidin-4-ylcarbonyl)morpholine

There total 3 articles about 4-(Piperidin-4-ylcarbonyl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: tert-butyl 4-(morpholin-4-oyl)piperidine-1-carboxylic acid ester

: 63214-57-3
(morpholin-4-yl)(piperidin-4-yl)methanone

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; methanol; at 20 ℃; for 1.5h;
DOI:10.1021/jm501436m

Reference yield:

: 757949-38-5
4-(piperidine-1-carbonyl)-piperidine-1-carboxylic acid tert-butyl ester

: 63214-57-3
(morpholin-4-yl)(piperidin-4-yl)methanone

Guidance literature:: With hydrogenchloride; In methanol; at 20 ℃; for 3h; Temperature;

Reference yield:

: 84358-13-4,174286-31-8
N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid

: 63214-57-3
(morpholin-4-yl)(piperidin-4-yl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 16 h / 20 °C

2: hydrogenchloride / methanol / 16 h / 20 °C

With hydrogenchloride; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In methanol; N,N-dimethyl-formamide;