2-methyloctahydro-2H-pyrazino[1,2-a]pyrazine

Base Information

Chemical Name:2-methyloctahydro-2H-pyrazino[1,2-a]pyrazine
CAS No.:63285-62-1
Molecular Formula:C8H17N3
Molecular Weight:155.24
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90493866
Nikkaji Number:J371.834D
Mol file:63285-62-1.mol

Synonyms:63285-62-1;2-methyloctahydro-2H-pyrazino[1,2-a]pyrazine;2-methyl-1,3,4,6,7,8,9,9a-octahydropyrazino[1,2-a]pyrazine;2-Methyloctahydro-1H-pyrazino[1,2-a]pyrazine;2H-Pyrazino[1,2-a]pyrazine,octahydro-2-methyl-(9CI);SCHEMBL20774258;DTXSID90493866;MFCD11878615;AKOS022185662;SB74206;CS-0454413;EN300-6767782;2-methyl-octahydro-1H-pyrazino[1,2-a]piperazine

Suppliers and Price of 2-methyloctahydro-2H-pyrazino[1,2-a]pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-methyloctahydro-2H-pyrazino[1,2-a]pyrazine
10mg
$ 45.00

ChemBridge Corporation
2-methyloctahydro-2H-pyrazino[1,2-a]pyrazine 95%
250 mg
$ 225.00

AccelPharmtech
octahydro-2-methyl-2H-Pyrazino[1,2-a]pyrazine 97.00%
25G
$ 11400.00

AccelPharmtech
octahydro-2-methyl-2H-Pyrazino[1,2-a]pyrazine 97.00%
1G
$ 3510.00

Total 4 raw suppliers

Chemical Property of 2-methyloctahydro-2H-pyrazino[1,2-a]pyrazine

Chemical Property:

PSA：18.51000
LogP:-0.58980
XLogP3:-0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:155.142247555
Heavy Atom Count:11
Complexity:137

Purity/Quality:

99% ^*data from raw suppliers

2-methyloctahydro-2H-pyrazino[1,2-a]pyrazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1CCN2CCNCC2C1

Technology Process of 2-methyloctahydro-2H-pyrazino[1,2-a]pyrazine

There total 7 articles about 2-methyloctahydro-2H-pyrazino[1,2-a]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 134749-50-1
2-methyl-8-(trifluoromethylsulfonyl)octahydropyrazino<1,2-a>pyrazine-1,4-dione

: 63285-62-1
2-methyloctahydro-2H-pyrazino[1,2-a]pyrazine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 18h; Heating;

Reference yield:

: 134749-45-4
ethyl 1-benzylpiperazine-2-carboxylate

: 63285-62-1
2-methyloctahydro-2H-pyrazino[1,2-a]pyrazine

Guidance literature:: Multi-step reaction with 5 steps

1: 94 percent / Et₃N / CH₂Cl₂ / 1.) -75 deg C, 1 h, 2.) -> r.t.

2: 69 percent / H₂ / 10percent Pd-C / acetic acid / 1 h / 2068.6 Torr / Ambient temperature

3: 82 percent / NaHCO₃ / CH₂Cl₂ / 3 h / 0 °C

4: 52 percent / ethanol / 1 h / 0 °C

5: 58 percent / LiAlH₄ / tetrahydrofuran / 18 h / Heating

With lithium aluminium tetrahydride; hydrogen; sodium hydrogencarbonate; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol; dichloromethane; acetic acid;

Reference yield:

: 134749-46-5
1-benzyl-2-ethoxycarbonyl-4-(trifluoromethylsulfonyl)piperazine

: 63285-62-1
2-methyloctahydro-2H-pyrazino[1,2-a]pyrazine

Guidance literature:: Multi-step reaction with 4 steps

1: 69 percent / H₂ / 10percent Pd-C / acetic acid / 1 h / 2068.6 Torr / Ambient temperature

2: 82 percent / NaHCO₃ / CH₂Cl₂ / 3 h / 0 °C

3: 52 percent / ethanol / 1 h / 0 °C

4: 58 percent / LiAlH₄ / tetrahydrofuran / 18 h / Heating

With lithium aluminium tetrahydride; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol; dichloromethane; acetic acid;