2-Methylpyrido[2,3-b]pyrazine 1,4-dioxide

Base Information

Chemical Name:2-Methylpyrido[2,3-b]pyrazine 1,4-dioxide
CAS No.:64204-11-1
Molecular Formula:C₈H₇N₃O₂
Molecular Weight:177.162
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40503742
Wikidata:Q82357761

Synonyms:64204-11-1;2-methylpyrido[2,3-b]pyrazine 1,4-dioxide;2-methyl-1-oxidopyrido[2,3-b]pyrazin-4-ium 4-oxide;DTXSID40503742;2-Methyl-4-oxopyrido[2,3-b]pyrazin-4-ium-1(4H)-olate

Suppliers and Price of 2-Methylpyrido[2,3-b]pyrazine 1,4-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Methylpyrido[2,3-b]pyrazine 1,4-dioxide

Chemical Property:

Melting Point:221 °C (decomp)
Boiling Point:418.5±55.0 °C(Predicted)
PKA:1.13±0.30(Predicted)
PSA：63.81000
Density:1.42±0.1 g/cm3(Predicted)
LogP:1.40020
XLogP3:-0.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:177.053826475
Heavy Atom Count:13
Complexity:264

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C[N+](=O)C2=C(N1[O-])C=CC=N2

Technology Process of 2-Methylpyrido[2,3-b]pyrazine 1,4-dioxide

There total 4 articles about 2-Methylpyrido[2,3-b]pyrazine 1,4-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 27808-52-2
1,2,5-Oxadiazolo<3,4-b>pyridin-1-oxid

: 67-64-1
acetone

: 64204-11-1
2-Methyl-pyrido<2,3-b>pyrazin-1,4-dioxid

Guidance literature:: With morpholine; In acetone;

Reference yield:

: 4214-75-9
2-amino-3-nitropyridine

: 64204-11-1
2-Methyl-pyrido<2,3-b>pyrazin-1,4-dioxid

Guidance literature:: Multi-step reaction with 2 steps

1: 82 percent / phenyliodosodiacetate / benzene / 2 h / 60 °C

2: 1.) morpholine, molecular sieve (4 Angstroem) / 1.) reflux, 2 h; 2.) reflux, 1 h

With morpholine; [bis(acetoxy)iodo]benzene; 4 A molecular sieve; In benzene;
DOI:10.1007/BF00903236

Reference yield:

: 73721-27-4
4-nitrotetrazolo<1,5-a>pyridine

: 64204-11-1
2-Methyl-pyrido<2,3-b>pyrazin-1,4-dioxid

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / dioxane / 15 h / Heating

2: 1.) morpholine, molecular sieve (4 Angstroem) / 1.) reflux, 2 h; 2.) reflux, 1 h

With morpholine; 4 A molecular sieve; In 1,4-dioxane;
DOI:10.1007/BF00903236