3-Methylpyridine-2-carbonyl chloride

Base Information

Chemical Name:3-Methylpyridine-2-carbonyl chloride
CAS No.:64588-88-1
Molecular Formula:C7H6 Cl N O
Molecular Weight:155.58164
Hs Code.:2933399090
DSSTox Substance ID:DTXSID00607972
Wikidata:Q82507077
Mol file:64588-88-1.mol

Synonyms:64588-88-1;3-Methylpyridine-2-carbonyl chloride;2-Pyridinecarbonylchloride, 3-methyl-;2-PYRIDINECARBONYL CHLORIDE, 3-METHYL-;3-methyl-pyridine-2-carbonyl chloride;3-methylpicolinic acid chloride;SCHEMBL1340289;DTXSID00607972;HUBOTQVVYJUKOV-UHFFFAOYSA-N;AKOS011625925;DA-23313

Suppliers and Price of 3-Methylpyridine-2-carbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-Methylpyridine-2-carbonylchloride 95%
1g
$ 672.00

Labseeker
2-PYRIDINECARBONYLCHLORIDE,3-METHYL- 95
10g
$ 1717.00

Labseeker
2-PYRIDINECARBONYLCHLORIDE,3-METHYL- 95
2g
$ 1217.00

Atlantic Research Chemicals
3-Methylpyridine-2-carbonylchloride 95%
1gm:
$ 236.82

Total 3 raw suppliers

Chemical Property of 3-Methylpyridine-2-carbonyl chloride

Chemical Property:

PSA：29.96000
LogP:1.76900
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:155.0137915
Heavy Atom Count:10
Complexity:138

Purity/Quality:

99% ^*data from raw suppliers

3-Methylpyridine-2-carbonylchloride 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N=CC=C1)C(=O)Cl

Technology Process of 3-Methylpyridine-2-carbonyl chloride

There total 3 articles about 3-Methylpyridine-2-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4021-07-2
3-methyl-pyridine-2-carboxylic acid

: 64588-88-1
3-methyl-2-pyridinecarboxylic acid chloride

Guidance literature:: With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 25 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jm900173b

Reference yield:

: 609-71-2
2-hydroxy-3-carboxypyridine

: 64588-88-1
3-methyl-2-pyridinecarboxylic acid chloride

Guidance literature:: With thionyl chloride;

Reference yield:

: 20970-75-6
2-cyano-3-methylpyridine

: 64588-88-1
3-methyl-2-pyridinecarboxylic acid chloride

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / water / 4 h / Reflux

2: thionyl chloride / N,N-dimethyl-formamide; 1,2-dichloro-ethane / 4 h / Reflux; Inert atmosphere

With thionyl chloride; sodium hydroxide; In water; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1002/chem.201804161