1-Methyl-2-cyclohexene-1-carboxylic acid

Base Information

Chemical Name:1-Methyl-2-cyclohexene-1-carboxylic acid
CAS No.:64326-19-8
Molecular Formula:C8H12 O2
Molecular Weight:140.182
Hs Code.:2916209090
DSSTox Substance ID:DTXSID50392381
Mol file:64326-19-8.mol

Synonyms:1-methylcyclohex-2-ene-1-carboxylic acid;64326-19-8;1-Methyl-2-cyclohexene-1-carboxylic acid;ghl.PD_Mitscher_leg0.16;starbld0005275;SCHEMBL1285848;DTXSID50392381;AKOS006377065;EN300-6735281;1-METHYL-2-CYCLOHEXENE-1-CARBOXYLIC ACID , 99%;Z1205494611

Suppliers and Price of 1-Methyl-2-cyclohexene-1-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
1-Methyl-2-cyclohexene-1-carboxylicacid
10g
$ 4160.00

AK Scientific
1-Methyl-2-cyclohexene-1-carboxylicacid
2.5g
$ 1949.00

AK Scientific
1-Methyl-2-cyclohexene-1-carboxylicacid
250mg
$ 567.00

Total 4 raw suppliers

Chemical Property of 1-Methyl-2-cyclohexene-1-carboxylic acid

Chemical Property:

PSA：37.30000
LogP:1.81740
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:140.083729621
Heavy Atom Count:10
Complexity:172

Purity/Quality:

99% ^*data from raw suppliers

1-Methyl-2-cyclohexene-1-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CCCC=C1)C(=O)O

Technology Process of 1-Methyl-2-cyclohexene-1-carboxylic acid

There total 7 articles about 1-Methyl-2-cyclohexene-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 69216-87-1
2-Mesyloxy-1-methyl-1-aethoxycarbonyl-cyclohexan

: 64326-19-8
rac-1-methylcyclohex-2-ene-1-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 110 °C

2: water; sodium hydroxide / ethanol / 2 h / Reflux

With water; 1,8-diazabicyclo[5.4.0]undec-7-ene; sodium hydroxide; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/ja204255e

Reference yield:

: 66088-42-4
ethyl 1-methyl-2-hydroxycyclohexanecarboxylate

: 64326-19-8
rac-1-methylcyclohex-2-ene-1-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane

2: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 110 °C

3: water; sodium hydroxide / ethanol / 2 h / Reflux

With water; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; sodium hydroxide; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja204255e

Reference yield:

: 1655-07-8
ethyl 2-oxocyclohexane carboxylate

: 64326-19-8
rac-1-methylcyclohex-2-ene-1-carboxylic acid

Guidance literature:: Multi-step reaction with 5 steps

1: sodium hydride / tetrahydrofuran

2: sodium tetrahydroborate / methanol / -78 °C

3: triethylamine / dichloromethane

4: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 110 °C

5: water; sodium hydroxide / ethanol / 2 h / Reflux

With sodium tetrahydroborate; water; sodium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; sodium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja204255e