1-(Bromomethyl)-4-fluoro-2-iodobenzene

Base Information

Chemical Name:1-(Bromomethyl)-4-fluoro-2-iodobenzene
CAS No.:70931-59-8
Molecular Formula:C7H5BrFI
Molecular Weight:314.924
Hs Code.:2903999090
DSSTox Substance ID:DTXSID30510309
Wikidata:Q82368503
Mol file:70931-59-8.mol

Synonyms:1-(bromomethyl)-4-fluoro-2-iodobenzene;70931-59-8;1-BROMOMETHYL-4-FLUORO-2-IODO-BENZENE;4-fluoro-2-iodobenzyl bromide;SCHEMBL2525744;DTXSID30510309;BPSKLIWSZVNGFO-UHFFFAOYSA-N;BS-53132;CS-0526909;FT-0720178;1-(bromomethyl)-4-fluoranyl-2-iodanyl-benzene;EN300-2978054;A837030

Suppliers and Price of 1-(Bromomethyl)-4-fluoro-2-iodobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(BROMOMETHYL)-4-FLUORO-2-IODOBENZENE 95.00%
5MG
$ 502.81

Ambeed
1-(Bromomethyl)-4-fluoro-2-iodobenzene 97%
1g
$ 90.00

Ambeed
1-(Bromomethyl)-4-fluoro-2-iodobenzene 97%
250mg
$ 38.00

Ambeed
1-(Bromomethyl)-4-fluoro-2-iodobenzene 97%
100mg
$ 27.00

Ambeed
1-(Bromomethyl)-4-fluoro-2-iodobenzene 97%
5g
$ 323.00

Alichem
4-Fluoro-2-iodobenzylbromide
1g
$ 1445.30

Alichem
4-Fluoro-2-iodobenzylbromide
500mg
$ 863.90

Alichem
4-Fluoro-2-iodobenzylbromide
250mg
$ 499.20

AHH
1-(bromomethyl)-4-fluoro-2-iodobenzene 97%
1g
$ 225.00

Total 13 raw suppliers

Chemical Property of 1-(Bromomethyl)-4-fluoro-2-iodobenzene

Chemical Property:

Boiling Point:277.5±25.0 °C(Predicted)
PSA：0.00000
Density:2.168±0.06 g/cm3(Predicted)
LogP:3.32520
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:313.86034
Heavy Atom Count:10
Complexity:110

Purity/Quality:

98%min ^*data from raw suppliers

1-(BROMOMETHYL)-4-FLUORO-2-IODOBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)I)CBr

Technology Process of 1-(Bromomethyl)-4-fluoro-2-iodobenzene

There total 5 articles about 1-(Bromomethyl)-4-fluoro-2-iodobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: (4-fluoro-2-iodophenyl)methanol

: 70931-59-8
1-(bromomethyl)-4-fluoro-2-iodobenzene

Guidance literature:: With 1H-imidazole; bromine; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/acs.orglett.8b01927

Reference yield: 71.0%

: 13194-67-7
4-fluoro-2-iodotoluene

: 70931-59-8
1-(bromomethyl)-4-fluoro-2-iodobenzene

Guidance literature:: With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane;
DOI:10.1016/j.bmcl.2006.11.080

Reference yield:

: 56096-89-0
4-fluoro-2-iodobenzoic acid

: 70931-59-8
1-(bromomethyl)-4-fluoro-2-iodobenzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: borane-THF / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

1.2: 2 h / Reflux; Inert atmosphere

2.1: triphenylphosphine; bromine; 1H-imidazole / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

With 1H-imidazole; borane-THF; bromine; triphenylphosphine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/acs.orglett.8b01927