2-amino-6-[(2-hydroxyethyl)amino]pyrimidin-4(1H)-one

Base Information

• Chemical Name: 2-amino-6-[(2-hydroxyethyl)amino]pyrimidin-4(1H)-one
• CAS No.: 1077-04-9
• Molecular Formula: C₆H₁₀N₄O₂
• Molecular Weight: 170.171
• Mol file: 1077-04-9.mol

Synonyms:4(1H)-Pyrimidinone,2-amino-6-[(2-hydroxyethyl)amino]- (9CI); 4(3H)-Pyrimidinone,2-amino-6-[(2-hydroxyethyl)amino]- (7CI,8CI); NSC 55460

Chemical Property of 2-amino-6-[(2-hydroxyethyl)amino]pyrimidin-4(1H)-one

Chemical Property:

• Vapor Pressure: 9.29E-08mmHg at 25°C
• Boiling Point: 391.7°C at 760 mmHg
• Flash Point: 190.7°C
• Density: 1.6g/cm³

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-amino-6-[(2-hydroxyethyl)amino]pyrimidin-4(1H)-one

There total 3 articles about 2-amino-6-[(2-hydroxyethyl)amino]pyrimidin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

6-chloroisocytosine (1194-21-4) + ethanolamine (141-43-5) → 2-amino-6-(2-hydroxy-ethylamino)-3H-pyrimidin-4-one (1077-04-9)

Guidance literature:

In 2-methoxy-ethanol; water; for 6h; Heating;

Reference yield:

→ 2-Amino-4-(2'-hydroxyethyl-amino)-6-hydroxy-pyrimidin (1077-04-9)

Guidance literature:

2-Amino-4-chlor-6-hydroxy-pyrimidin, Monoethanolamin;

Reference yield:

→ 2-amino-6-(2-hydroxy-ethylamino)-3H-pyrimidin-4-one (1077-04-9)

Guidance literature:

DOI:10.1007/BF00920916

upstream raw materials:

6-chloroisocytosine

ethanolamine