1-(4-Tert-butylbenzyl)-1,3-dihydrobenzimidazol-2-one

Base Information

Chemical Name:1-(4-Tert-butylbenzyl)-1,3-dihydrobenzimidazol-2-one
CAS No.:537702-33-3
Molecular Formula:C₁₈H₂₀N₂O
Molecular Weight:280.37
Hs Code.:
DSSTox Substance ID:DTXSID20353848
Wikidata:Q82131662
Mol file:537702-33-3.mol

Synonyms:537702-33-3;1-(4-tert-butylbenzyl)-1,3-dihydrobenzimidazol-2-one;1-(4-tert-butylbenzyl)-1,3-dihydro-2H-benzimidazol-2-one;1-(4-(tert-Butyl)benzyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one;Oprea1_408674;SCHEMBL4594603;DTXSID20353848;STK844277;AKOS001692897

Suppliers and Price of 1-(4-Tert-butylbenzyl)-1,3-dihydrobenzimidazol-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-(4-Tert-butylbenzyl)-1,3-dihydrobenzimidazol-2-one

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:280.157563266
Heavy Atom Count:21
Complexity:379

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC=C(C=C1)CN2C3=CC=CC=C3NC2=O

Technology Process of 1-(4-Tert-butylbenzyl)-1,3-dihydrobenzimidazol-2-one

There total 4 articles about 1-(4-Tert-butylbenzyl)-1,3-dihydrobenzimidazol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: 615-16-7
1,3-dihydro-2H-benzimidazol-2-one

: 18880-00-7
1-(bromomethyl)-4-(1,1-dimethylethyl)benzene

: 1,3-bis-(4-tert-butylbenzyl)-1,3-dihydro-benzimidazol-2-one

: 537702-33-3
1-(4-tert-butylbenzyl)-1,3-dihydro-benzimidazol-2-one

Guidance literature:: With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 75 ℃; for 2h;

Reference yield:

: C₁₇H₂₂N₂

: 57-13-6
urea

: 537702-33-3
1-(4-tert-butylbenzyl)-1,3-dihydro-benzimidazol-2-one

Guidance literature:: In N,N-dimethyl-formamide; at 160 ℃; for 5h;
DOI:10.1016/j.bmcl.2010.07.086

Reference yield:

: 88-74-4
2-nitro-aniline

: 537702-33-3
1-(4-tert-butylbenzyl)-1,3-dihydro-benzimidazol-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 120 °C

2: palladium 10% on activated carbon; hydrogen / methanol / 3 h / 20 °C

3: N,N-dimethyl-formamide / 0.5 h / 200 °C

With palladium 10% on activated carbon; hydrogen; potassium carbonate; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2014.07.038 DOI:10.1016/j.ejmech.2014.07.038