2,2,2-Trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate

Base Information

Chemical Name:2,2,2-Trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate
CAS No.:50778-57-9
Molecular Formula:C13H9 F9 O4
Molecular Weight:400.198
Hs Code.:
European Community (EC) Number:610-568-7
DSSTox Substance ID:DTXSID20461093
Wikidata:Q82285341

Synonyms:50778-57-9;2,2,2-trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate;Benzoic acid,2,5-bis(2,2,2-trifluoroethoxy)-, 2,2,2-trifluoroethyl ester;starbld0006612;SCHEMBL6794207;DTXSID20461093;2,2,2-TRIFLUOROETHYL2,5-BIS(2,2,2-TRIFLUORO-ETHOXY)-BENZOATE;AKOS030254730;FT-0675519;trifluoroethanol 2,5-bis-trifluoroethoxybenzoate

Suppliers and Price of 2,2,2-Trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,2,2-Trifluoroethyl2,5-Bis(2,2,2-trifluoroethoxy)benzoate
250mg
$ 425.00

TRC
2,2,2-Trifluoroethyl2,5-Bis(2,2,2-trifluoroethoxy)benzoate
1g
$ 1550.00

TRC
2,2,2-Trifluoroethyl2,5-Bis(2,2,2-trifluoroethoxy)benzoate
500mg
$ 805.00

American Custom Chemicals Corporation
2,2,2-TRIFLUOROETHYL 2,5-BIS(2,2,2-TRIFLUOROETHOXY)BENZOATE 95.00%
1G
$ 1593.90

American Custom Chemicals Corporation
2,2,2-TRIFLUOROETHYL 2,5-BIS(2,2,2-TRIFLUOROETHOXY)BENZOATE 95.00%
100MG
$ 704.55

American Custom Chemicals Corporation
2,2,2-TRIFLUOROETHYL 2,5-BIS(2,2,2-TRIFLUOROETHOXY)BENZOATE 95.00%
1MG
$ 289.80

Total 10 raw suppliers

Chemical Property of 2,2,2-Trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate

Chemical Property:

Vapor Pressure:0.000674mmHg at 25°C
Boiling Point:308.6oC at 760 mmHg
Flash Point:135.9oC
PSA：44.76000
Density:1.46g/cm3
LogP:4.28790
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol
XLogP3:5.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:13
Rotatable Bond Count:7
Exact Mass:400.03571222
Heavy Atom Count:26
Complexity:458

Purity/Quality:

99%, ^*data from raw suppliers

2,2,2-Trifluoroethyl2,5-Bis(2,2,2-trifluoroethoxy)benzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1OCC(F)(F)F)C(=O)OCC(F)(F)F)OCC(F)(F)F
Uses Intermediate in the production of antiarrhythmic N-(Piperidylalkyl)trifluoroethoxybenzamides. Possible Flecainide impurity.

Technology Process of 2,2,2-Trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate

There total 2 articles about 2,2,2-Trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6226-25-1
2,2,2-trifluoroethyl trifluoromethanesulphonate

: 490-79-9
2,5-dihydroxybenzoic acid.

: 50778-57-9
2,2,2-trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate

Guidance literature:: With potassium hydrogencarbonate; In water; acetone;

Reference yield:

: 50778-57-9
2,2,2-trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate

Guidance literature:: 2.2.2-Trifluoroethyl-trifluoromethansulfonat, K2CO3, sd. Acn., 2.5-Dihydroxybenzoesaeure in Acn.;
DOI:10.1021/jm00245a017

Reference yield:

: 22990-77-8,111478-74-1,111478-77-4
C-piperidin-2-yl-methylamine

: 50778-57-9
2,2,2-trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate

: 57415-44-8
flecainide hydrochloride

Guidance literature:: C-piperidin-2-yl-methylamine; 2,2,2-trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate; In benzene; at 45 ℃; for 40h;

With hydrogenchloride; In isopropyl alcohol; at 2 ℃;