3-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID

Base Information

• Chemical Name: 3-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID
• CAS No.: 354548-73-5
• Molecular Formula: C₈H₅BrN₂O₂
• Molecular Weight: 241.044
• Hs Code.: 2933990090
• Mol file: 354548-73-5.mol

Synonyms:3-Bromoimidazo[1,2-a]-2-pyridinecarboxylic acid;3-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid;3-Bromo-4-hydroimidazo[1,2-a]pyridine-2-carboxylic acid;

Chemical Property of 3-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID

Chemical Property:

• Refractive Index: 1.728
• PSA: 54.60000
• Density: 1.899 g/cm³
• LogP: 1.79500
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

3-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID

There total 3 articles about 3-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-aminopyridine (504-29-0) → C8H5BrN2O2 (354548-73-5)

Guidance literature:

Multi-step reaction with 3 steps

1: acetonitrile

2: bromine / acetic acid

3: ethanol; sodium hydroxide

With ethanol; bromine; sodium hydroxide; In acetic acid; acetonitrile;

DOI:10.1016/j.bmcl.2012.01.080

Reference yield:

ethyl 3-imidazo[1,2-a]pyridine-2-carboxylate (38922-77-9) → C8H5BrN2O2 (354548-73-5)

Guidance literature:

Multi-step reaction with 2 steps

1: bromine / acetic acid

2: ethanol; sodium hydroxide

With ethanol; bromine; sodium hydroxide; In acetic acid;

DOI:10.1016/j.bmcl.2012.01.080

Reference yield:

ethyl 3-bromoimidazo<1,2-a>pyridin-2-carboxylate (143982-54-1) → C8H5BrN2O2 (354548-73-5)

Guidance literature:

With ethanol; sodium hydroxide;

DOI:10.1016/j.bmcl.2012.01.080

upstream raw materials:

2-aminopyridine

ethyl 3-imidazo[1,2-a]pyridine-2-carboxylate

ethyl 3-bromoimidazo<1,2-a>pyridin-2-carboxylate

Downstream raw materials:

C₂₀H₁₉BrF₂N₄O

Refernces