2,5-Dibromoterephthalic acid diethyl ester

Base Information

• Chemical Name: 2,5-Dibromoterephthalic acid diethyl ester
• CAS No.: 18013-97-3
• Molecular Formula: C12H12 Br2 O4
• Molecular Weight: 380.033
• Hs Code.: 2917399090
• Mol file: 18013-97-3.mol

Synonyms:1,4-Benzenedicarboxylicacid, 2,5-dibromo-, diethyl ester (9CI); Terephthalic acid, 2,5-dibromo-,diethyl ester (8CI); Diethyl 1,4-dibromo-2,5-benzenedicarboxylate; Diethyl2,5-dibromoterephthalate

Chemical Property of 2,5-Dibromoterephthalic acid diethyl ester

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 127.0 to 131.0 °C
• Boiling Point: 388.312oC at 760 mmHg
• Flash Point: 188.644oC
• PSA: 52.60000
• Density: 1.648g/cm3
• LogP: 3.56500
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

Diethyl 2,5-Dibromoterephthalate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,5-Dibromoterephthalic acid diethyl ester

There total 7 articles about 2,5-Dibromoterephthalic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethanol (64-17-5) + 2,5-dibromoterephtalic acid (13731-82-3) → 2,5-dibromo-terephthalic acid diethyl ester (18013-97-3)

Guidance literature:

2,5-dibromoterephtalic acid; With thionyl chloride; for 4h; Reflux;

ethanol; In tetrahydrofuran; for 10h;

DOI:10.1039/c9ce00568d

Reference yield:

thiophene boronic acid (6165-68-0) → 2,5-dibromo-terephthalic acid diethyl ester (18013-97-3)

Guidance literature:

With potassium carbonate; In toluene;

Reference yield:

2,5-dibromo-p-xylene (1074-24-4) → 2,5-dibromo-terephthalic acid diethyl ester (18013-97-3)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydroxide; potassium permanganate / H₂O / 12 h / Heating

2: SOCl₂ / 4 h / Heating

3: 2.1 g / 4 h / Heating

With sodium hydroxide; potassium permanganate; thionyl chloride; In water;

DOI:10.1039/b517067b

upstream raw materials:

2,5-dibromoterephtalic acid

ethanol

3,6-dibromo-2,5-phenylenedi(carboxylic acid chloride)

2,5-dibromo-p-xylene

Downstream raw materials:

diethyl 2,5-bis(9,9-dioctyl-9H-fluoren-2-yl)terephthalate

C₄₄H₃₃BrS₂

C₅₂H₄₃NS₂

C₅₃H₄₃NOS₂

Refernces

• 1、 Al-Fayaad, Hydar A.,Athukorala Arachchige, Kasun S.,Clegg, Jack K.. "A heterofunctional ligand approach for the preparation of high connectivity coordination polymers: Combining a "bridge" and "pillar" in one ligand". . p. 5310 - 5315. Retrieved 2020/09/03.
• 2、 -. "Mechanochromic diethyl terephthalate compound, as well as preparation method and application thereof". Paragraph 0035; 0036. . Retrieved 2019/01/08.