2-bromo-3-(ethylsulfonyl)-pyridine

Base Information

• Chemical Name: 2-bromo-3-(ethylsulfonyl)-pyridine
• CAS No.: 124589-98-6
• Molecular Formula: C₇H₈BrNO₂S
• Molecular Weight: 250.116
• Mol file: 124589-98-6.mol

Synonyms:2-Bromo-3-(ethylsulfonyl)pyridine;

Chemical Property of 2-bromo-3-(ethylsulfonyl)-pyridine

Chemical Property:

• Boiling Point: 405.4 °C at 760 mmHg
• Flash Point: 199 °C
• PSA: 55.41000
• Density: 1.591 g/cm³
• LogP: 2.71850

Purity/Quality:

98%Min ^*data from raw suppliers

2-BROMO-3-(ETHYLSULFONYL)-PYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-bromo-3-(ethylsulfonyl)-pyridine

There total 6 articles about 2-bromo-3-(ethylsulfonyl)-pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.9%

2-(ethanesulfonyl)acetonitrile (13654-62-1) + 3-dimethylaminoacrolein (927-63-9) → 2-bromo-3-ethylsulfonylpyridine (124589-98-6)

Guidance literature:

2-(ethanesulfonyl)acetonitrile; 3-dimethylaminoacrolein; With 1-dodecyl-3-methylimidazol-1-ium chloride; at 90 ℃; for 3h;

With hydrogen bromide;

Reference yield: 93.3%

2-ethylsulfonyl-5-(N,N-diethylamino)-2,4-pentadienenitrile → 2-bromo-3-ethylsulfonylpyridine (124589-98-6)

Guidance literature:

With hydrogen bromide; at 20 ℃; for 0.166667h; Green chemistry;

Reference yield:

C9H14N2O2S → 2-bromo-3-ethylsulfonylpyridine (124589-98-6)

Guidance literature:

With hydrogen bromide; In dichloromethane; at 25 ℃;

upstream raw materials:

malonaldehydebis(dimethylacetal)

2-(ethanesulfonyl)acetonitrile

3-dimethylaminoacrolein

Refernces

• 1、 -. "HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD CONTROLLING AGENT CONTAINING SAME". Paragraph 1516-1519. . Retrieved 2019/11/11.
• 2、 -. "Method for synthesizing 2-halo-3-substited alkylsulfonyl pyridine and intermediate compound thereof through microwave method". Paragraph 0018; 0096; 0097; 0098; 0099. . Retrieved 2017/07/15.