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Usage

Uses

Used in Pharmaceutical Industry:
Ethylsulfonylacetonitrile is used as an intermediate in the production of pharmaceuticals, playing a crucial role in the synthesis of various bioactive compounds. It contributes to the development of antiviral and anti-inflammatory drugs, showcasing its importance in medicinal chemistry for creating effective treatments.
Used in Agrochemical Industry:
In the agrochemical sector, ethylsulfonylacetonitrile is also utilized as an intermediate, indicating its broad application in the synthesis of compounds that are vital for agricultural chemicals, potentially aiding in pest control and crop protection.
Used in Dye and Pigment Manufacturing:
Ethylsulfonylacetonitrile is employed in the manufacturing of dyes and pigments, underlining its role in the coloration of various products, from textiles to industrial applications, where colorfast and vibrant dyes are required.
Used in Polymer Production:
ethylsulfonylacetonitrile is also used in the production of polymers, highlighting its significance in the creation of a wide range of polymeric materials with diverse properties and applications, from plastics to advanced materials used in various industries.
Used as a Reagent in Organic Chemistry:
Ethylsulfonylacetonitrile is recognized as a versatile reagent in organic chemistry, due to its capacity to participate in multiple chemical reactions, making it an indispensable tool for chemists in the synthesis of complex organic molecules.
It is imperative to handle ethylsulfonylacetonitrile with care, given its hazardous nature if not used properly, ensuring safety in laboratories and industrial settings where it is employed.

Upstream product

• 20035-08-9 sodium ethanesulfinate 
• 107-14-2 chloroacetonitrile 
• 594-44-5 Ethanesulfonyl chloride 
• 53250-09-2 2-(ethylthio)acetonitrile 

Downstream Products

• 124589-98-6 2-bromo-3-ethylsulfonylpyridine 

Relevant academic research and scientific papers

METHOD FOR MANUFACTURING CYANOPYRIDINE COMPOUND

PROBLEM TO BE SOLVED: To provide a novel method for manufacturing a cyanopyridine compound. SOLUTION: There is provided a method for manufacturing a cyanopyridine compound represented by the formula (1) by reacting a compound represented by the formula (4) and a cyanating agent. (4), (1), where R1 represents an alkyl group having 1 to 6 carbon atoms or a phenyl group which may have an alkyl group having 1 to 6 carbon atoms, the alkyl group having 1 to 6 carbon atoms may have a halogen atom, R2, R3 and R4 represent each independently a hydrogen atom or an alkyl group having 1 to 6 carbon atoms which may have a halogen atom, X2 represents a halogen atom and n represents an integer of 0 to 2. COPYRIGHT: (C)2016,JPO&INPIT

Synthesis and biological evaluation of triazolothienopyrimidine derivatives as novel HIV-1 replication inhibitors

We identified a novel class of triazolothienopyrimidine (TTPM) compounds as potent HIV-1 replication inhibitors during a high-throughput screening campaign that evaluated more than 200,000 compounds using a cell-based full replication assay. Herein, we report the optimization of the antiviral activity in a cell-based assay system leading to the discovery of aryl-substituted TTPM derivatives (38, 44, and 45), which exhibited significant inhibition of HIV-1 replication with acceptable safety margins. These novel and potent TTPMs could serve as leads for further development.

Selective oxidation of sulfides to sulfoxides/sulfones by 30% hydrogen peroxide

A selective and efficient procedure for the oxidation of various sulfides with sodium tungstate dihydrate with 30% hydrogen peroxide in the presence of trioctylmethylammonium dihydrogen phosphate, respectively, to the corresponding sulfoxides and sulfones is reported. The oxidation reaction is carried out at -5 to 0 °C in the presence of hydroxypropyl -β cyclodextrins for sulfoxides or at 50-60 °C for sulfones. The mild reaction conditions, easy workup, and good yields of the products are the major advantages of this method. Copyright Taylor and Francis Group, LLC 2012.