5-[[[[(phenylmethoxy)carbonyl]amino]carbonyl]amino]-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid diphenylmethyl ester

Base Information

• Chemical Name: 5-[[[[(phenylmethoxy)carbonyl]amino]carbonyl]amino]-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid diphenylmethyl ester
• CAS No.: 151416-18-1
• Molecular Formula: C₃₁H₃₀N₄O₉
• Molecular Weight: 602.601
• Mol file: 151416-18-1.mol

Synonyms:

Chemical Property of 5-[[[[(phenylmethoxy)carbonyl]amino]carbonyl]amino]-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid diphenylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-[[[[(phenylmethoxy)carbonyl]amino]carbonyl]amino]-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid diphenylmethyl ester

There total 6 articles about 5-[[[[(phenylmethoxy)carbonyl]amino]carbonyl]amino]-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid diphenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C37H36N4O12 (151416-16-9) → 5-[[[[(phenylmethoxy)carbonyl]amino]carbonyl]amino]-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid diphenylmethyl ester (151416-18-1)

Guidance literature:

With potassium hydroxide; In methanol; Yield given;

DOI:10.1016/S0040-4039(00)79951-5

Reference yield:

benzyloxycarbonyl isocyanate (69032-16-2) → 5-[[[[(phenylmethoxy)carbonyl]amino]carbonyl]amino]-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid diphenylmethyl ester (151416-18-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,2-dichloroethane

2: KOH / methanol

With potassium hydroxide; 1,2-dichloro-ethane; In methanol;

DOI:10.1016/S0040-4039(00)79951-5

Reference yield:

5-amino-1-(2,3,5-tris-O-acetyl-β-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid diphenylmethyl ester (151416-15-8) → 5-[[[[(phenylmethoxy)carbonyl]amino]carbonyl]amino]-1-(β-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid diphenylmethyl ester (151416-18-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,2-dichloroethane

2: KOH / methanol

With potassium hydroxide; 1,2-dichloro-ethane; In methanol;

DOI:10.1016/S0040-4039(00)79951-5

upstream raw materials:

C₃₇H₃₆N₄O₁₂

benzyloxycarbonyl isocyanate

5-amino-1-(2,3,5-tris-O-acetyl-β-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid diphenylmethyl ester

diazodiphenylmethane

Downstream raw materials:

[3-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-7-oxo-3,7-dihydro-imidazo[4,5-d][1,3]oxazin-5-yl]-carbamic acid benzyl ester

C₁₈H₂₀N₄O₉