Technology Process of C24H31ClFN5O
There total 12 articles about C24H31ClFN5O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
1,4-dioxane;
at 20 ℃;
DOI:10.1021/jm301024w
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: ozone / dichloromethane / 0.25 h / -78 °C
1.2: 1 h / 20 °C
1.3: 20 h / 0 °C
2.1: Resolution of racemate
3.1: Nonafluorobutanesulfonyl fluoride; triethylamine hydrofluoride
4.1: hydrogenchloride / dichloromethane; 1,4-dioxane / 12 h
5.1: N-ethyl-N,N-diisopropylamine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / 4 h / 0 - 20 °C
6.1: hydrogenchloride / 1,4-dioxane / 20 °C
With
hydrogenchloride; Nonafluorobutanesulfonyl fluoride; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; ozone; triethylamine hydrofluoride; N-ethyl-N,N-diisopropylamine;
In
1,4-dioxane; dichloromethane;
DOI:10.1021/jm301024w
- Guidance literature:
-
Multi-step reaction with 4 steps
1: Nonafluorobutanesulfonyl fluoride; triethylamine hydrofluoride
2: hydrogenchloride / dichloromethane; 1,4-dioxane / 12 h
3: N-ethyl-N,N-diisopropylamine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / 4 h / 0 - 20 °C
4: hydrogenchloride / 1,4-dioxane / 20 °C
With
hydrogenchloride; Nonafluorobutanesulfonyl fluoride; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine hydrofluoride; N-ethyl-N,N-diisopropylamine;
In
1,4-dioxane; dichloromethane;
DOI:10.1021/jm301024w
