C₄₀H₆₆O₆Si

Base Information

• Chemical Name: C₄₀H₆₆O₆Si
• CAS No.: 945908-25-8
• Molecular Formula: C₄₀H₆₆O₆Si
• Molecular Weight: 671.046
• Mol file: 945908-25-8.mol

Synonyms:

Chemical Property of C₄₀H₆₆O₆Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₀H₆₆O₆Si

There total 5 articles about C₄₀H₆₆O₆Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2-{(2R,3S,4S,5S,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-[(S)-4-(tert-butyl-dimethyl-silanyloxy)-3-methyl-butyl]-3,5-dimethyl-tetrahydro-pyran-2-yl}-3,4,6-trimethoxy-5-methyl-phenyl)-acetaldehyde (717916-62-6) → C40H66O6Si (945908-25-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 90 percent / CrCl₂ / NiCl₂ / dimethylformamide / 3 h / 60 °C

2: 71 percent / IBX; pyridine / dimethylsulfoxide; tetrahydrofuran / 3 h / 20 - 45 °C

3: 82 percent / PPTS / methanol / 28 h / 20 °C

4: IBX / dimethylsulfoxide / 6.5 h / 20 - 45 °C

5: n-BuLi / tetrahydrofuran / 10 h / 20 °C

With pyridine; chromium dichloride; n-butyllithium; pyridinium p-toluenesulfonate; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; nickel dichloride; In tetrahydrofuran; methanol; dimethyl sulfoxide; N,N-dimethyl-formamide; 1: Noyaki-Hiyama-Kishi coupling / 5: Wittig methylenation;

DOI:10.1246/cl.2007.726

Reference yield:

C38H62O8Si + Methyltriphenylphosphonium bromide (1779-49-3) → C40H66O6Si (945908-25-8)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at 20 ℃; for 10h;

DOI:10.1246/cl.2007.726

Reference yield:

C50H96O8Si3 (945908-23-6) → C40H66O6Si (945908-25-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 71 percent / IBX; pyridine / dimethylsulfoxide; tetrahydrofuran / 3 h / 20 - 45 °C

2: 82 percent / PPTS / methanol / 28 h / 20 °C

3: IBX / dimethylsulfoxide / 6.5 h / 20 - 45 °C

4: n-BuLi / tetrahydrofuran / 10 h / 20 °C

With pyridine; n-butyllithium; pyridinium p-toluenesulfonate; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; methanol; dimethyl sulfoxide; 4: Wittig methylenation;

DOI:10.1246/cl.2007.726

upstream raw materials:

Methyltriphenylphosphonium bromide

C₅₀H₉₆O₈Si₃

C₅₀H₉₄O₈Si₃

C₃₈H₆₆O₈Si