Technology Process of 14,17-Cycloethano-norcodeinondimethylacetal-benzyl-hydroxyd
There total 9 articles about 14,17-Cycloethano-norcodeinondimethylacetal-benzyl-hydroxyd which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 92 percent / K2CO3 / acetone / 0.5 h / Heating
2: 83 percent / bromacetamide / CH2Cl2
3: 61 percent / 4 N NaOH, H2 / Pd/C (10 percent Pd) / methanol / 3.5 h
4: 64 percent / xylene / 12 h / Heating
5: 1) 1 M LiAlH4, 2) NaBH4 / 1) THF, reflux, 2 h, 2) methanol
6: 84 percent / methanol / 0.17 h
7: 93 percent / methanol / 3 h / Heating
8: 72 percent / Ag2O, H2O / 0.5 h
With
sodium hydroxide; sodium tetrahydroborate; lithium aluminium tetrahydride; bromo-acetic acid amide; water; hydrogen; potassium carbonate; silver(l) oxide;
10% palladium on active carbon;
In
methanol; dichloromethane; acetone; xylene;
DOI:10.1007/BF00812333
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 61 percent / 4 N NaOH, H2 / Pd/C (10 percent Pd) / methanol / 3.5 h
2: 64 percent / xylene / 12 h / Heating
3: 1) 1 M LiAlH4, 2) NaBH4 / 1) THF, reflux, 2 h, 2) methanol
4: 84 percent / methanol / 0.17 h
5: 93 percent / methanol / 3 h / Heating
6: 72 percent / Ag2O, H2O / 0.5 h
With
sodium hydroxide; sodium tetrahydroborate; lithium aluminium tetrahydride; water; hydrogen; silver(l) oxide;
10% palladium on active carbon;
In
methanol; xylene;
DOI:10.1007/BF00812333
