Carbonic acid allyl ester (R)-1-[(2S,3S)-1-(tert-butyl-dimethyl-silanyl)-2-((S)-1-fluoro-1-methyl-2-oxo-2-phenyl-ethyl)-4-oxo-azetidin-3-yl]-ethyl ester

Base Information

Chemical Name:Carbonic acid allyl ester (R)-1-[(2S,3S)-1-(tert-butyl-dimethyl-silanyl)-2-((S)-1-fluoro-1-methyl-2-oxo-2-phenyl-ethyl)-4-oxo-azetidin-3-yl]-ethyl ester
CAS No.:168780-23-2
Molecular Formula:C₂₄H₃₄FNO₅Si
Molecular Weight:463.622
Hs Code.:

Carbonic acid allyl ester (R)-1-[(2S,3S)-1-(tert-butyl-dimethyl-silanyl)-2-((S)-1-fluoro-1-methyl-2-oxo-2-phenyl-ethyl)-4-oxo-azetidin-3-yl]-ethyl ester

Synonyms:

Suppliers and Price of Carbonic acid allyl ester (R)-1-[(2S,3S)-1-(tert-butyl-dimethyl-silanyl)-2-((S)-1-fluoro-1-methyl-2-oxo-2-phenyl-ethyl)-4-oxo-azetidin-3-yl]-ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Carbonic acid allyl ester (R)-1-[(2S,3S)-1-(tert-butyl-dimethyl-silanyl)-2-((S)-1-fluoro-1-methyl-2-oxo-2-phenyl-ethyl)-4-oxo-azetidin-3-yl]-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbonic acid allyl ester (R)-1-[(2S,3S)-1-(tert-butyl-dimethyl-silanyl)-2-((S)-1-fluoro-1-methyl-2-oxo-2-phenyl-ethyl)-4-oxo-azetidin-3-yl]-ethyl ester

There total 9 articles about Carbonic acid allyl ester (R)-1-[(2S,3S)-1-(tert-butyl-dimethyl-silanyl)-2-((S)-1-fluoro-1-methyl-2-oxo-2-phenyl-ethyl)-4-oxo-azetidin-3-yl]-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87037-97-6
methyl (2R)-2-[(2S,3S)-3-{(1R)-1-(t-butyldimethylsilyloxy)ethyl}-4-oxoazetidin-2-yl]propionate

: 168780-23-2
Carbonic acid allyl ester (R)-1-[(2S,3S)-1-(tert-butyl-dimethyl-silanyl)-2-((S)-1-fluoro-1-methyl-2-oxo-2-phenyl-ethyl)-4-oxo-azetidin-3-yl]-ethyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: 1.) LDA, 2.) N-fluoro-N-(exo-2-norbornyl)-p-toluenesulfonamide / 1.) HMPA, THF, -78 deg C, 2.) HMPA, THF, from -78 deg C to RT

2: 1N aq. LiOH

3: PPh₃ / CH₂Cl₂

4: Et₃N / CH₂Cl₂

5: tetrahydrofuran

6: BF₃*Et₂O / acetonitrile

7: DMAP / CH₂Cl₂

With dmap; lithium hydroxide; N-fluoro-N-(exo-2-norbornyl)-p-toluenesulfonamide; boron trifluoride diethyl etherate; triethylamine; triphenylphosphine; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; acetonitrile;

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 168780-23-2
Carbonic acid allyl ester (R)-1-[(2S,3S)-1-(tert-butyl-dimethyl-silanyl)-2-((S)-1-fluoro-1-methyl-2-oxo-2-phenyl-ethyl)-4-oxo-azetidin-3-yl]-ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: Et₃N / CH₂Cl₂

2: tetrahydrofuran

3: BF₃*Et₂O / acetonitrile

4: DMAP / CH₂Cl₂

With dmap; boron trifluoride diethyl etherate; triethylamine; In tetrahydrofuran; dichloromethane; acetonitrile;

Reference yield:

: 168960-99-4
(S)-2-{(2S,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-2-fluoro-propionic acid methyl ester

: 168780-23-2
Carbonic acid allyl ester (R)-1-[(2S,3S)-1-(tert-butyl-dimethyl-silanyl)-2-((S)-1-fluoro-1-methyl-2-oxo-2-phenyl-ethyl)-4-oxo-azetidin-3-yl]-ethyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 1N aq. LiOH

2: PPh₃ / CH₂Cl₂

3: Et₃N / CH₂Cl₂

4: tetrahydrofuran

5: BF₃*Et₂O / acetonitrile

6: DMAP / CH₂Cl₂

With dmap; lithium hydroxide; boron trifluoride diethyl etherate; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane; acetonitrile;