Technology Process of 3-Penten-1-yne, 5-(1-ethoxyethoxy)-3-methyl-, (3E)-
There total 1 articles about 3-Penten-1-yne, 5-(1-ethoxyethoxy)-3-methyl-, (3E)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
1.) 5 deg C, 2.) RT, 10 min;
DOI:10.1021/jo00132a028
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) n-BuLi / 1.) ether, hexane, RT, 15 min, 2.) 22 deg C, 1 h
2: 72 percent / H2, potassium carbonate / Lindlar catalyst / toluene / 3 h / 20 °C / 760 Torr
3: PBr3 / diethyl ether / 0.08 h / Ambient temperature
4: 69 percent / benzene / Heating
5: 78 percent / NaOCH3 / CH2Cl2; methanol / 1 h / -10 °C
With
n-butyllithium; hydrogen; sodium methylate; phosphorus tribromide; potassium carbonate;
Lindlar's catalyst;
In
methanol; diethyl ether; dichloromethane; toluene; benzene;
DOI:10.1021/jo00132a028
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) n-BuLi / 1.) ether, hexane, - 60 deg C, 2.) ether, RT, 45 min
2: H2SO4(5percent) / acetone / 1.5 h / Ambient temperature
3: 90 percent / H2, quinoline, potassium carbonate / Lindlar catalyst / ethyl acetate / 2.17 h / 21 °C / 760 Torr
4: PBr3 / diethyl ether / 1.) -60 deg C, 1 h, 2.) RT
5: benzene / 1.5 h / Heating
With
quinoline; n-butyllithium; sulfuric acid; hydrogen; phosphorus tribromide; potassium carbonate;
Lindlar's catalyst;
In
diethyl ether; ethyl acetate; acetone; benzene;
DOI:10.1021/jo00132a029
