4-Bromo-2-formylthiazole

Base Information

Chemical Name:4-Bromo-2-formylthiazole
CAS No.:167366-05-4
Molecular Formula:C4H2BrNOS
Molecular Weight:192.036
Hs Code.:2934100090
European Community (EC) Number:627-487-8
DSSTox Substance ID:DTXSID00376797
Nikkaji Number:J2.730.162B
Wikidata:Q72512873
Mol file:167366-05-4.mol

Synonyms:4-Bromo-2-formylthiazole;167366-05-4;4-bromothiazole-2-carbaldehyde;4-bromo-1,3-thiazole-2-carbaldehyde;4-bromothiazole-2-carboxaldehyde;2-Thiazolecarboxaldehyde, 4-bromo-;MFCD06660122;2-Thiazolecarboxaldehyde,4-bromo-;SCHEMBL30401;4-bromo-2-thiazolecarboxaldehyde;DTXSID00376797;JDUXMFGFGCJNGO-UHFFFAOYSA-N;AKOS005256368;AM84573;CS-W010714;PB41180;PS-4862;4-Bromo-1,3-thiazole-2-carboxaldehyde;4-Bromothiazole-2-carboxaldehyde, 96%;AC-25737;BP-10406;SY011906;FT-0685286;A19601;EN300-110042;J-508549;J-508552;W-200543;4-Bromo-2-formylthiazole, 4-Bromothiazole-2-carbaldehyde

Suppliers and Price of 4-Bromo-2-formylthiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Bromo-2-formylthiazole
100mg
$ 75.00

SynQuest Laboratories
4-Bromo-1,3-thiazole-2-carboxaldehyde
25 g
$ 632.00

SynQuest Laboratories
4-Bromo-1,3-thiazole-2-carboxaldehyde
5 g
$ 160.00

SynQuest Laboratories
4-Bromo-1,3-thiazole-2-carboxaldehyde
250 mg
$ 32.00

Sigma-Aldrich
4-Bromothiazole-2-carboxaldehyde 96%
1g
$ 95.30

Matrix Scientific
4-Bromo-2-formylthiazole 97%
500mg
$ 76.00

Matrix Scientific
4-Bromo-2-formylthiazole 97%
1g
$ 126.00

Matrix Scientific
4-Bromo-2-formylthiazole 97%
5g
$ 488.00

Labseeker
4-BROMO-2-FORMYLTHIAZOLE 97
10g
$ 400.00

Frontier Specialty Chemicals
4-Bromo-2-formylthiazole 98%
25g
$ 225.00

Total 53 raw suppliers

Chemical Property of 4-Bromo-2-formylthiazole

Chemical Property:

Melting Point:66-70 °C
Boiling Point:288.113 °C at 760 mmHg
PKA:-2.33±0.10(Predicted)
Flash Point:128.046 °C
PSA：58.20000
Density:1.921 g/cm³
LogP:1.71810
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:190.90405
Heavy Atom Count:8
Complexity:100

Purity/Quality:

98% ^*data from raw suppliers

4-Bromo-2-formylthiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-36-43
Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=C(N=C(S1)C=O)Br

Technology Process of 4-Bromo-2-formylthiazole

There total 4 articles about 4-Bromo-2-formylthiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 4175-77-3
2,4-dibromo-1,3-thiazole

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 167366-05-4
4-bromo-1,3-thiazole-2-carbaldehyde

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; at -78 - 25 ℃; for 2h;

Reference yield: 61.0%

: 4394-85-8
4-morpholinecarboxaldehyde

: 4175-77-3
2,4-dibromo-1,3-thiazole

: 167366-05-4
4-bromo-1,3-thiazole-2-carbaldehyde

Guidance literature:: 2,4-dibromo-1,3-thiazole; With TurboGrignard; In tetrahydrofuran; at -78 ℃; for 0.25h; Inert atmosphere;

4-morpholinecarboxaldehyde; In tetrahydrofuran; at -78 - 0 ℃; for 1.66667h; Inert atmosphere;
DOI:10.1016/j.tetasy.2012.03.014

Reference yield:

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 167366-05-4
4-bromo-1,3-thiazole-2-carbaldehyde

Guidance literature:: 2,4-dibromo-1,3-thiazole; With n-butyllithium; In hexanes; diethyl ether; at -78 ℃; for 0.5h; Cooling with acetone-dry ice;

N,N-dimethyl-formamide; In hexanes; diethyl ether; at -78 - 20 ℃; for 2.5h;