(2S,3S,3aR*)-2,3-dimethyl hexahydropyrrolo[1,2-b][1,2]oxazole-2,3-dicarboxylate

Base Information

Chemical Name:(2S*,3S*,3aR*)-2,3-dimethyl hexahydropyrrolo[1,2-b][1,2]oxazole-2,3-dicarboxylate
CAS No.:56783-28-9
Molecular Formula:C₁₀H₁₅NO₅
Molecular Weight:229.233
Hs Code.:

Synonyms:

Suppliers and Price of (2S*,3S*,3aR*)-2,3-dimethyl hexahydropyrrolo[1,2-b][1,2]oxazole-2,3-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S*,3S*,3aR*)-2,3-dimethyl hexahydropyrrolo[1,2-b][1,2]oxazole-2,3-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S*,3S*,3aR*)-2,3-dimethyl hexahydropyrrolo[1,2-b][1,2]oxazole-2,3-dicarboxylate

There total 2 articles about (2S*,3S*,3aR*)-2,3-dimethyl hexahydropyrrolo[1,2-b][1,2]oxazole-2,3-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6139-84-0
4-chlorobutyraldehyde

: 624-49-7
dimethylfumarate

: 56783-28-9,56816-54-7,113083-34-4,126575-65-3,126575-66-4
(2S*,3S*,3aS*)-2,3-dimethyl hexahydropyrrolo[1,2-b][1,2]oxazole-2,3-dicarboxylate

: 56783-28-9,56816-54-7,113083-34-4,126575-65-3,126575-66-4
(2S*,3S*,3aR*)-2,3-dimethyl hexahydropyrrolo[1,2-b][1,2]oxazole-2,3-dicarboxylate

Guidance literature:: 4-chlorobutyraldehyde; With hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine; In toluene; at 60 ℃; for 0.5h;

dimethylfumarate; In toluene; for 3.5h; Time; Overall yield = 87 %; Overall yield = 200 mg; Reflux;
DOI:10.1039/C6OB01871H

Reference yield:

: 6139-84-0
4-chlorobutyraldehyde

: 624-49-7
dimethylfumarate

: 56783-28-9,56816-54-7,113083-34-4,126575-65-3,126575-66-4
(2S*,3S*,3aS*)-2,3-dimethyl hexahydropyrrolo[1,2-b][1,2]oxazole-2,3-dicarboxylate

: 56783-28-9,56816-54-7,113083-34-4,126575-65-3,126575-66-4
(2S*,3S*,3aR*)-2,3-dimethyl hexahydropyrrolo[1,2-b][1,2]oxazole-2,3-dicarboxylate

Guidance literature:: 4-chlorobutyraldehyde; With hydroxylamine hydrochloride; N-ethyl-N,N-diisopropylamine; In toluene; at 60 ℃; for 0.5h;

dimethylfumarate; In toluene; for 3.5h; Time; Overall yield = 87 %; Overall yield = 200 mg; Reflux;
DOI:10.1039/C6OB01871H

Reference yield:

: 56783-28-9,56816-54-7,113083-34-4,126575-65-3,126575-66-4
(2S*,3S*)-2,3-dimethyl hexahydropyrrolo[1,2-b][1,2]oxazole-2,3-dicarboxylate

: 21823-66-5,21823-73-4,21823-74-5,21823-78-9,21824-61-3,21850-64-6,70494-70-1,85647-44-5,85848-68-6,90205-20-2
(+/-)-Macronecin

Guidance literature:: Multi-step reaction with 2 steps

1: zinc; acetic acid / water / 22 h / Reflux

2: lithium aluminium tetrahydride / tetrahydrofuran / 17 h / Reflux

With lithium aluminium tetrahydride; acetic acid; zinc; In tetrahydrofuran; water;
DOI:10.1039/C6OB01871H