ethyl 5,8-dimethoxy-4-oxo-1,4-dihydroquinoline-2-carboxylate

Base Information

Chemical Name:ethyl 5,8-dimethoxy-4-oxo-1,4-dihydroquinoline-2-carboxylate
CAS No.:5288-23-3
Molecular Formula:C₁₄H₁₅NO₅
Molecular Weight:277.277
Hs Code.:
Mol file:5288-23-3.mol

Synonyms:Quinaldicacid, 4-hydroxy-5,8-dimethoxy-, ethyl ester (7CI,8CI); NSC 12817

Suppliers and Price of ethyl 5,8-dimethoxy-4-oxo-1,4-dihydroquinoline-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of ethyl 5,8-dimethoxy-4-oxo-1,4-dihydroquinoline-2-carboxylate

Chemical Property:

Vapor Pressure:4.66E-08mmHg at 25°C
Boiling Point:443.4°C at 760 mmHg
Flash Point:221.9°C
Density:1.247g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ethyl 5,8-dimethoxy-4-oxo-1,4-dihydroquinoline-2-carboxylate

There total 2 articles about ethyl 5,8-dimethoxy-4-oxo-1,4-dihydroquinoline-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 102-56-7,102526-87-4
2,5-dimethoxyaniline

: 108-56-5
diethyl oxaloacetate

: 5288-23-3
4-Hydroxy-5,8-dimethoxy-chinolin-2-carbonsaeureethylester

Guidance literature:: Erhitzen des Reaktionsprodukts in Paraffinoel auf 240grad;
DOI:10.1021/ja01167a521

Reference yield:

: 5288-23-3
4-Hydroxy-5,8-dimethoxy-chinolin-2-carbonsaeureethylester

Guidance literature:: 11c, Cyclisierung;
DOI:10.1002/jlac.197619760217

Reference yield:

: 5288-23-3
4-Hydroxy-5,8-dimethoxy-chinolin-2-carbonsaeureethylester

: 5428-11-5
4-chloro-5,8-dimethoxyquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: aqueous NaOH

2: diphenyl ether

3: phosphoryl chloride

With sodium hydroxide; diphenylether; trichlorophosphate;
DOI:10.1021/ja01167a521