2-Methyl-1-propenylmagnesium bromide

Base Information

• Chemical Name: 2-Methyl-1-propenylmagnesium bromide
• CAS No.: 38614-36-7
• Molecular Formula: C4H7BrMg
• Molecular Weight: 159.309
• Hs Code.: 29319090
• European Community (EC) Number: 684-507-8
• Mol file: 38614-36-7.mol

Synonyms:2-methyl-1-propenylmagnesium bromide;38614-36-7;(2-methylprop-1-enyl)magnesium bromide;2-Methyl-1-propenyl magnesium bromide;SCHEMBL22727;2-methylpropenylmagnesium bromide;2-methyl-propenylmagnesium bromide;2-methylpropenyl magnesium bromide;BKVIQODYSREJQH-UHFFFAOYSA-M;2-methyl propenyl magnesium bromide;2-methylprop-1-enylmagnesium bromide;MFCD00209600;AKOS030228186;Methyl1-benzylpiperidine-3-carboxylate;J-802096;2-Methyl-1-propenylmagnesium bromide, 0.5M (8.35% w/w) in THF

Chemical Property of 2-Methyl-1-propenylmagnesium bromide

Chemical Property:

• Flash Point: 5 °F
• PSA: 0.00000
• Density: 0.952 g/mL at 25 °C
• LogP: 2.30500
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 157.95815
• Heavy Atom Count: 6
• Complexity: 30.5

Purity/Quality:

97% ^*data from raw suppliers

2-Methyl-1-propenylmagnesium bromide solution 0.5 M in THF ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F;C
• Hazard Codes: F,C,Xn
• Statements: 11-14/15-19-20/21/22-34-37-40-36/37/38-15
• Safety Statements: 16-26-27-36/37/39-45-43-36/37

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(=[CH-])C.[Mg+2].[Br-]
• Uses: 2-Methyl-1-propenylmagnesium bromide(0.5?M in THF) is a reagent used in many chemical reactions such as in the preparation of biaryls, alkylarenes, alkenylarenes, alkynylalkenones via nucleophilic addition.Used in the study of palladium-catalyzed coupling with aryl tosylates. Used in a synthesis of (2S,3S)-3′-fluoroisoleucine. 2-Methyl-1-propenylmagnesium bromide can be used in a study of a palladium-catalyzed coupling with aryl tosylates.

Technology Process of 2-Methyl-1-propenylmagnesium bromide

There total 3 articles about 2-Methyl-1-propenylmagnesium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-1-propenylbromide (3017-69-4) → 2-methylpropen-1-ylmagnesium bromide (38614-36-7)

Guidance literature:

With magnesium; ethylene dibromide; In tetrahydrofuran; at 60 ℃; for 3h; Inert atmosphere;

DOI:10.1021/jacs.8b03549

Reference yield:

1-(p-tolylsulfonyl)bicyclo<1.1.0>butane (86537-30-6) → 2-methylpropen-1-ylmagnesium bromide (38614-36-7) + 1-Methyl-4-[3-(2-methyl-propenyl)-cyclobutanesulfonyl]-benzene (86537-36-2)

Guidance literature:

With copper(I) bromide dimethylsulfide complex; In tetrahydrofuran; at 20 ℃; for 1h; Yield given. Yields of byproduct given;

DOI:10.1021/jo00216a028

Reference yield:

→ 2-methylpropen-1-ylmagnesium bromide (38614-36-7)

Guidance literature:

upstream raw materials:

1-(p-tolylsulfonyl)bicyclo<1.1.0>butane

2-methyl-1-propenylbromide

Downstream raw materials:

3-methyl-2-buten-1-ol

(2-methyl-propenyl)-triphenyl-silane

diethyl-(3-methyl-1-phenyl-but-2-enyl)-amine

3-Methylbutenoic acid