H₂N-YALPET-OMe

Base Information

• Chemical Name: H₂N-YALPET-OMe
• CAS No.: 1419234-25-5
• Molecular Formula: C₃₃H₅₀N₆O₁₁
• Molecular Weight: 706.794
• Mol file: 1419234-25-5.mol

Synonyms:

Chemical Property of H₂N-YALPET-OMe

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of H₂N-YALPET-OMe

There total 1 articles about H₂N-YALPET-OMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyloxycarbonylmethyl (2S,3R)-3-tertbutyloxy-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)butanoate + methyl iodide (74-88-4) → H2N-YALPET-OMe (1419234-25-5)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide;

DOI:10.1002/anie.201204538

Reference yield: 30.0%

H2N-YALPET-OMe (1419234-25-5) + H2N-GGSEFG-COOH (1419234-19-7) → H2N-YALPETGGSEFG-COOH (1419234-20-0)

Guidance literature:

With sortase A; sodium chloride; calcium chloride; In aq. buffer; at 37 ℃; for 8h; Enzymatic reaction;

DOI:10.1002/anie.201204538

Reference yield:

H2N-YALPET-OMe (1419234-25-5) → H2N-YALPETG-CONH2 (1419234-17-5)

Guidance literature:

Multi-step reaction with 2 steps

1: sortase A; calcium chloride; sodium chloride / aq. buffer / 8 h / 37 °C / Enzymatic reaction

2: sortase A; calcium chloride; sodium chloride / aq. buffer / 37 °C / pH 7.5 / Enzymatic reaction

With sortase A; sodium chloride; calcium chloride; In aq. buffer;

DOI:10.1002/anie.201204538

upstream raw materials:

methyl iodide

Downstream raw materials:

H₂N-YALPETG-CONH₂

H₂N-YALPETGGSEFG-COOH

Refernces