Technology Process of potassium trifluoro(quinolin-4-yl)borate
There total 3 articles about potassium trifluoro(quinolin-4-yl)borate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
4-chloroquinoline;
With
tetrahydroxydiboron; 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); N-ethyl-N,N-diisopropylamine; triphenylphosphine;
In
ethanol;
at 80 ℃;
for 12h;
Inert atmosphere;
Sealed tube;
With
potassium hydrogen difluoride;
In
methanol; ethanol; water;
at 0 - 20 ℃;
for 0.5h;
DOI:10.1021/jo401104y
- Guidance literature:
-
With
potassium hydrogen difluoride;
In
methanol; ethanol; water;
at 0 - 20 ℃;
for 0.5h;
DOI:10.1021/jo401104y
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tetrahydroxydiboron; 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); triphenylphosphine; N-ethyl-N,N-diisopropylamine / ethanol / 4 h / 80 °C / Inert atmosphere; Sealed tube
2: potassium hydrogen difluoride / ethanol; methanol; water / 0.5 h / 0 - 20 °C
With
potassium hydrogen difluoride; tetrahydroxydiboron; 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); N-ethyl-N,N-diisopropylamine; triphenylphosphine;
In
methanol; ethanol; water;
1: |Miyaura Borylation Reaction;
DOI:10.1021/jo401104y
