Methyl (2-methyl-3-oxopiperazin-2-yl)acetate

Base Information

Chemical Name:Methyl (2-methyl-3-oxopiperazin-2-yl)acetate
CAS No.:534603-48-0
Molecular Formula:C₈H₁₄N₂O₃
Molecular Weight:186.211
Hs Code.:
DSSTox Substance ID:DTXSID40551869
Nikkaji Number:J1.871.120F
Mol file:534603-48-0.mol

Synonyms:534603-48-0;methyl 2-(2-methyl-3-oxopiperazin-2-yl)acetate;methyl (2-methyl-3-oxopiperazin-2-yl)acetate;METHYL 2-(2-METHYL-3-OXO-2-PIPERAZINYL)ACETATE;SCHEMBL3541093;2-Piperazineaceticacid,2-methyl-3-oxo-,methylester(9CI);DTXSID40551869;AKOS000319524;AKOS022060836;VS-07440;CS-0317659;methyl2-(2-methyl-3-oxopiperazin-2-yl)acetate

Suppliers and Price of Methyl (2-methyl-3-oxopiperazin-2-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl2-(2-methyl-3-oxo-2-piperazinyl)acetate
10mg
$ 45.00

Matrix Scientific
Methyl 2-(2-methyl-3-oxo-2-piperazinyl)acetate
1g
$ 306.00

Matrix Scientific
Methyl 2-(2-methyl-3-oxo-2-piperazinyl)acetate
500mg
$ 199.00

Crysdot
Methyl2-(2-methyl-3-oxopiperazin-2-yl)acetate 97%
5g
$ 704.00

American Custom Chemicals Corporation
METHYL 2-(2-METHYL-3-OXO-2-PIPERAZINYL)ACETATE 95.00%
500MG
$ 350.70

AK Scientific
Methyl2-(2-methyl-3-oxo-2-piperazinyl)acetate
1g
$ 463.00

Total 2 raw suppliers

Chemical Property of Methyl (2-methyl-3-oxopiperazin-2-yl)acetate

Chemical Property:

Boiling Point:343.1±27.0 °C(Predicted)
PKA:14.83±0.40(Predicted)
Density:1.088±0.06 g/cm3(Predicted)
XLogP3:-1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:186.10044231
Heavy Atom Count:13
Complexity:229

Purity/Quality:

98%min ^*data from raw suppliers

Methyl2-(2-methyl-3-oxo-2-piperazinyl)acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(C(=O)NCCN1)CC(=O)OC

Technology Process of Methyl (2-methyl-3-oxopiperazin-2-yl)acetate

There total 1 articles about Methyl (2-methyl-3-oxopiperazin-2-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 617-54-9
citraconic acid dimethyl ester

: 107-15-3,85404-18-8
ethylenediamine

: 534603-48-0
methyl 2-[(2RS)-2-methyl-3-oxo-piperazin-2-yl]acetate

Guidance literature:: In methanol; at 25 ℃; for 24h;
DOI:10.1016/S0040-4039(03)00103-5

Reference yield:

: 534603-48-0
methyl 2-[(2RS)-2-methyl-3-oxo-piperazin-2-yl]acetate

: (9aS)-7-[2,6-difluoro-4-[2-(2-fluorophenyl)ethynyl]phenyl]-9a-methyl-2,3,4,9-tetrahydropyrazino[1,2-c]pyrimidine-1,6,8-trione

: (9aR)-7-[2,6-difluoro-4-[2-(2-fluorophenyl)ethynyl]phenyl]-9a-methyl-2,3,4,9-tetrahydropyrazino[1,2-c]pyrimidine-1,6,8-trione

Guidance literature:: Multi-step reaction with 3 steps

1.1: toluene / 1 h / 110 °C

1.2: 2 h / Reflux

2.1: bis-triphenylphosphine-palladium(II) chloride; triethylamine; triphenylphosphine; copper(l) iodide / tetrahydrofuran / 2 h / 50 °C / Inert atmosphere

3.1: Chiral AD column / ethanol; n-heptane

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; triphenylphosphine; In tetrahydrofuran; ethanol; n-heptane; toluene;