2-Methyl-5-nitro-1-benzenesulfonic acid 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide

Base Information

Chemical Name:2-Methyl-5-nitro-1-benzenesulfonic acid 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide
CAS No.:372196-67-3
Molecular Formula:C16H14BrN5O4S
Molecular Weight:452.288
Hs Code.:
Mol file:372196-67-3.mol

Synonyms:Benzenesulfonicacid, 2-methyl-5-nitro-, [(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]methylhydrazide(9CI);PIK 75;N'-[(1Z)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylidene]-N,2-dimethyl-5-nitrobenzenesulfonohydrazide;Benzenesulfonic acid, 2-methyl-5-nitro-, [(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]methylhydrazide;

Suppliers and Price of 2-Methyl-5-nitro-1-benzenesulfonic acid 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
PIK-75
1mg
$ 312.00

TRC
PIK-75
50mg
$ 340.00

Matrix Scientific
(E)-N'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazide 97%
250mg
$ 2160.00

Matrix Scientific
(E)-N'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazide 97%
100mg
$ 1080.00

DC Chemicals
PIK-75freebase >98%
1 g
$ 1200.00

CSNpharm
PIK-75
50mg
$ 300.00

CSNpharm
PIK-75
10mg
$ 100.00

CSNpharm
PIK-75
1mg
$ 36.00

Crysdot
N'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazide 95+%
250mg
$ 574.00

Crysdot
N'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazide 95+%
100mg
$ 359.00

Total 19 raw suppliers

Chemical Property of 2-Methyl-5-nitro-1-benzenesulfonic acid 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide

Chemical Property:

PSA：121.24000
Density:1.663 g/cm³
LogP:4.57200
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

97% ^*data from raw suppliers

PIK-75 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses PIK-75 is a p110α inhibitor, isoform-specific mutants at Ser773, and also potently inhibits DNA-PK.

Technology Process of 2-Methyl-5-nitro-1-benzenesulfonic acid 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide

There total 1 articles about 2-Methyl-5-nitro-1-benzenesulfonic acid 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

: 30384-96-4
6-bromoimidazo[1,2-a]pyridine-3-carbaldehyde

: 121-02-8
2-methyl-5-nitrobenzene-1-sulfonyl chloride

: 60-34-4
methylhydrazine

: 372196-67-3,1201670-42-9,945619-31-8
[2-methyl-5-nitro-1-benzenesulfonic acid 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide]

Guidance literature:: 6-bromoimidazo[1,2-a]pyridine-3-carbaldehyde; methylhydrazine; In ethanol; for 3h; Reflux;

2-methyl-5-nitrobenzene-1-sulfonyl chloride; With pyridine; at 20 ℃; for 4h;
DOI:10.1002/anie.201804917