Tert-butyl 2-ethynylpiperidine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 2-ethynylpiperidine-1-carboxylate
CAS No.:255864-58-5
Molecular Formula:C12H19 N O2
Molecular Weight:209.288
Hs Code.:2933399090
European Community (EC) Number:826-716-0
DSSTox Substance ID:DTXSID00578991
Nikkaji Number:J1.220.730A
Mol file:255864-58-5.mol

Synonyms:255864-58-5;TERT-BUTYL 2-ETHYNYLPIPERIDINE-1-CARBOXYLATE;1-Boc-2-Ethynylpiperidine;1-PIPERIDINECARBOXYLIC ACID, 2-ETHYNYL-, 1,1-DIMETHYLETHYL ESTER;2-Ethynyl-piperidine;SCHEMBL525478;DTXSID00578991;OLYLUYXEZAJXAC-UHFFFAOYSA-N;MFCD13189966;AKOS016002934;AB69489;AB74005;DS-13115;CS-0033654;F30052;EN300-1877537;A877544;TERT-BUTYL2-ETHYNYLPIPERIDINE-1-CARBOXYLATE;Z1505700699

Suppliers and Price of Tert-butyl 2-ethynylpiperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-Butyl2-Ethynylpiperidine-1-carboxylate
50mg
$ 45.00

SynChem
1-PIPERIDINECARBOXYLIC ACID, 2-ETHYNYL-, 1,1-DIMETHYLETHYL ESTER 95+%
1 g
$ 535.00

Crysdot
tert-Butyl2-ethynylpiperidine-1-carboxylate 97%
10g
$ 547.00

Crysdot
tert-Butyl2-ethynylpiperidine-1-carboxylate 97%
5g
$ 322.00

Chemenu
tert-butyl2-ethynylpiperidine-1-carboxylate 97%
10g
$ 516.00

Chemenu
tert-butyl2-ethynylpiperidine-1-carboxylate 97%
5g
$ 304.00

Biosynth Carbosynth
tert-Butyl 2-ethynylpiperidine-1-carboxylate
1 g
$ 233.00

Biosynth Carbosynth
tert-Butyl 2-ethynylpiperidine-1-carboxylate
250 mg
$ 77.50

Biosynth Carbosynth
tert-Butyl 2-ethynylpiperidine-1-carboxylate
500 mg
$ 135.00

Biosynth Carbosynth
tert-Butyl 2-ethynylpiperidine-1-carboxylate
2 g
$ 406.00

Total 28 raw suppliers

Chemical Property of Tert-butyl 2-ethynylpiperidine-1-carboxylate

Chemical Property:

Vapor Pressure:0.007mmHg at 25°C
Boiling Point:269.583oC at 760 mmHg
PKA:-3.09±0.40(Predicted)
Flash Point:116.84oC
PSA：29.54000
Density:1.02
LogP:2.34710
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:209.141578849
Heavy Atom Count:15
Complexity:282

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl2-Ethynylpiperidine-1-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCCCC1C#C

Technology Process of Tert-butyl 2-ethynylpiperidine-1-carboxylate

There total 4 articles about Tert-butyl 2-ethynylpiperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 255864-58-5
tert-butyl 2-ethynylpiperidine-1-carboxylate

Guidance literature:

Reference yield: 84.0%

: 56506-90-2
(dibromomethyl)(triphenyl)phosphonium bromide

: 157634-02-1,132910-78-2
tert-butyl 2-formylpiperidine-1-carboxylate

: 255864-58-5
tert-butyl 2-ethynylpiperidine-1-carboxylate

Guidance literature:: (dibromomethyl)(triphenyl)phosphonium bromide; tert-butyl 2-formylpiperidine-1-carboxylate; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 0.0833333h;

With n-butyllithium; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/S0040-4039(99)01830-4