56506-90-2

Usage

Uses

Used in Organic Synthesis:
(dibromomethyl)(triphenyl)phosphonium is used as a reactant for the preparation of various organic compounds. Its unique structure allows the dibromomethyl group to participate in nucleophilic substitution and addition reactions, which are fundamental in creating a diverse range of organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (dibromomethyl)(triphenyl)phosphonium is used as a building block for the synthesis of complex organic molecules that can have potential medicinal properties. Its ability to undergo various reactions makes it a valuable tool in the development of new drugs and pharmaceutical agents.
Used in Chemical Research:
(dibromomethyl)(triphenyl)phosphonium is also utilized in chemical research as a model compound to study the reactivity and behavior of quaternary phosphonium salts. This helps in understanding the underlying mechanisms of various organic reactions and contributes to the advancement of organic chemistry knowledge.
Used in Material Science:
In material science, (dibromomethyl)(triphenyl)phosphonium can be employed in the synthesis of new materials with specific properties. Its reactivity and the ability to form various organic compounds make it a candidate for developing materials with tailored characteristics for different applications.

Upstream product

• 75-25-2 Bromoform 
• 603-35-0 triphenylphosphine 
• 19493-09-5 Methylenetriphenylphosphorane 
• 558-13-4 carbon tetrabromide 
• 1779-58-4 (methyloxycarbonylmethyl)triphenylphosphonium bromide 
• 13504-77-3 methyl 2-bromo-2-(triphenylphosphanylidene)acetate 

Downstream Products

• 7533-73-5 triphenyl(triphenylphosphoranylidenemethyl)phosphonium bromide 
• 90766-67-9 1,1-dibromo-4-phenyl-1,3-butadiene 
• 766-96-1 4-bromo-1-ethynylbenzene 
• 1608-03-3 (E)-but-1-en-3-yn-1-ylbenzene 
• 935-14-8 1,4-diethynylbenzene 
• 17573-94-3 4-ethynyl-N,N-dimethylaniline 
• 255864-58-5 tert-butyl 2-ethynylpiperidine-1-carboxylate 
• 294634-72-3 (3,3-dibromoprop-2-enyl)benzene 
• 52956-06-6 (bromobuta-1,3-diyn-1-yl)benzene 
• 181214-43-7 (4,4-dibromobut-3-en-1-ynyl)benzene 
• 77295-67-1 1,4-bis(2,2-dibromoethenyl)benzene 
• 60512-57-4 1-(2,2-dibromovinyl)-4-methoxybenzene 
• 7436-90-0 2,2-dibromostyrene 
• 67396-36-5 (3-bromoprop-2-yn-1-yl)benzene 

Relevant academic research and scientific papers

Synthesis of 1,1-dibromo-1-alkenes from partially and unprotected aldoses

Partially and unprotected aldoses react with dibromomethylenetriphenylphosphorane, generated in situ from dibromomethyltriphenylphosphonium bromide in the presence of zinc, to give corresponding unsaturated Wittig adducts in good yields.

Synthesis of vinyliodides: Progress toward the total synthesis of a jatrophane diterpene

A noticeable effort toward the total synthesis of a jatrophane diterpene has been made via the synthesis of various vinyliodides utilizing highly stereoselective Tanino-Miyashita olefination reaction; and utilizing the dithiane moiety as an acyl anion equ

Stereoselective Total Synthesis of Atractylodemayne A, a Conjugated 2(E),8(Z),10(E)-Triene-4,6-diyne

The first total synthesis of the polyacetylene natural product atractylodemayne A is reported. Stereoselective construction of the conjugated 8(Z),10(E)-diene moiety was achieved through a tethered ring-closing metathesis approach, comprising a Ru-catalyz

ANTIBACTERIAL QUINAZOLINE-4(3H)-ONE DERIVATIVES

The invention relates to antibacterial compounds of formula I, wherein R1 is H or halogen; R2 is the group M; R3 is H or halogen; M is MA or MB wherein A is a bond or C≡C; R1A is H or halo

New photochromic dithienylethenes through a click chemistry approach

Symmetric dithienylethenes 9-12 bearing a variety of substituents were synthesized by a click chemistry approach. The starting material, diacetylene 4, was obtained through Wittig reaction of dialdehyde 1 with dibromomethyltriphenylphosphonium bromide (2) and subsequent treatment with a lithium base (Corey-Fuchs reaction). Triazoles 11 and 12 with covalently linked fluorophore moieties show reversible quenching of fluorescence in solution. A series of functional photochromic compounds based on dithienylethenes has been synthesized by utilizing a copper-catalyzed azide-alkyne click chemistry approach. Dithienylethenes substituted with fluorophores show reversible photoswitching of fluorescence upon irradiation with UV/Vis light. Copyright

Synthesis of glyco-1-ynitols via 1,1-dibromo-1-alkenes from partially and unprotected aldoses

We report the synthesis of 1,1-dibromo-1-alkenes from partially and unprotected aldoses and the synthesis of glyco-1-ynitols from these dibromocompounds. The 1,1-dibromo-1-alkenes were obtained by the reaction of dibromomethyl-triphenylphosphonium bromide

Asymmetric synthesis of the highly potent anti-metastatic prostacyclin analogue cicaprost and its isomer isocicaprost

An asymmetric synthesis of the anti-metastatic prostacyclin analogue cicaprost and a formal one of its isomer isocicaprost by a new route are described. A key step of these syntheses is the coupling of a chiral bicyclic C6-C14 ethynyl building block with

NOVEL REACTIONS OF PHOSPHONIUM YLIDES WITH PERHALOALKANES: FIRST EXAMPLES OF HALOPHILIC ATTACKS BY PHOSPHONIUM YLIDES AND A FACILE ROUTE TO α-HALOALKYLPHOSPHONIUM SALTS

Phosphonium ylides Ph3=CHR (R = H, CH3, C2H5, n-C3H7, n-C5H11) react readily with perhalofluoroalkanes to afford regiospecifically α-haloalkylphosphonium salts Ph3P+-CHXR Y- (X = I, Br, Cl) in good yields.These reactions reveal a new type of reactivity phosphonium ylides, i.e., the halophilic attack on C-X bonds, and may be useful for the regiospecific synthesis of substituted haloolefins via Wittig reaction.