(S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentanal

Base Information

Chemical Name:(S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentanal
CAS No.:152426-90-9
Molecular Formula:C₃₂H₅₄O₆S₂Si
Molecular Weight:626.995
Hs Code.:

(S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentanal

Synonyms:

Suppliers and Price of (S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentanal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentanal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentanal

There total 20 articles about (S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 152426-89-6
(S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentan-1-ol

: 152426-90-9
(S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentanal

Guidance literature:: With pyridine-SO₃ complex; dimethyl sulfoxide; triethylamine;
DOI:10.1016/S0040-4039(00)74063-9

Reference yield:

: 121352-88-3
[(2R,3R)-3-(2-Benzyloxy-1,1-dimethyl-ethyl)-oxiranyl]-methanol

: 152426-90-9
(S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentanal

Guidance literature:: Multi-step reaction with 8 steps

1: 96 percent / Red-Al / toluene

2: 98 percent / imidazole

3: 98 percent / H₂ / Pd-black / ethanol

4: 92 percent / Swern oxidation

5: 84 percent / MgBr₂*OEt₂ / diethyl ether

6: 1) t-BuLi, HMPA / 1) THF, -78 deg C

7: 92 percent / PPTS / methanol

8: 91 percent / SO₃*pyridine, DMSO, NEt₃

With 1H-imidazole; N,N,N,N,N,N-hexamethylphosphoric triamide; pyridine-SO₃ complex; hydrogen; tert.-butyl lithium; pyridinium p-toluenesulfonate; dimethyl sulfoxide; triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride; magnesium bromide; palladium; In methanol; diethyl ether; ethanol; toluene;
DOI:10.1016/S0040-4039(00)74063-9

Reference yield:

: 152426-81-8
(3S)-1-benzyloxy-2,2-dimethylpentane-3,5-diol

: 152426-90-9
(S)-4-[2-((2S,6R)-6-Benzyloxymethyl-4,4-dimethoxy-tetrahydro-pyran-2-ylmethyl)-[1,3]dithian-2-yl]-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentanal

Guidance literature:: Multi-step reaction with 7 steps

1: 98 percent / imidazole

2: 98 percent / H₂ / Pd-black / ethanol

3: 92 percent / Swern oxidation

4: 84 percent / MgBr₂*OEt₂ / diethyl ether

5: 1) t-BuLi, HMPA / 1) THF, -78 deg C

6: 92 percent / PPTS / methanol

7: 91 percent / SO₃*pyridine, DMSO, NEt₃

With 1H-imidazole; N,N,N,N,N,N-hexamethylphosphoric triamide; pyridine-SO₃ complex; hydrogen; tert.-butyl lithium; pyridinium p-toluenesulfonate; dimethyl sulfoxide; triethylamine; magnesium bromide; palladium; In methanol; diethyl ether; ethanol;
DOI:10.1016/S0040-4039(00)74063-9