(2-{4-[2-(Benzenesulfonyl)ethyl]phenyl}hydrazinyl)(oxo)acetic acid

Base Information

Chemical Name:(2-{4-[2-(Benzenesulfonyl)ethyl]phenyl}hydrazinyl)(oxo)acetic acid
CAS No.:868618-78-4
Molecular Formula:C₁₆H₁₆N₂O₅S
Molecular Weight:348.379
Hs Code.:
DSSTox Substance ID:DTXSID60583041
Wikidata:Q82474552

Synonyms:868618-78-4;(2-{4-[2-(Benzenesulfonyl)ethyl]phenyl}hydrazinyl)(oxo)acetic acid;2-[2-[4-[2-(benzenesulfonyl)ethyl]phenyl]hydrazinyl]-2-oxoacetic acid;DTXSID60583041;2-oxo-2-(2-(4-(2-(phenylsulfonyl)ethyl)phenyl)hydrazinyl)acetic acid

Suppliers and Price of (2-{4-[2-(Benzenesulfonyl)ethyl]phenyl}hydrazinyl)(oxo)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (2-{4-[2-(Benzenesulfonyl)ethyl]phenyl}hydrazinyl)(oxo)acetic acid

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:348.07799279
Heavy Atom Count:24
Complexity:529

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)S(=O)(=O)CCC2=CC=C(C=C2)NNC(=O)C(=O)O

Technology Process of (2-{4-[2-(Benzenesulfonyl)ethyl]phenyl}hydrazinyl)(oxo)acetic acid

There total 4 articles about (2-{4-[2-(Benzenesulfonyl)ethyl]phenyl}hydrazinyl)(oxo)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 148960-51-4
4-(2-benzenesulfonylethyl)phenylamine

: 50-81-7,98966-42-8
ascorbic acid

: 868618-78-4
oxo(2-{4-[2-(phenylsulfonyl)ethyl]phenyl}hydrazino)acetic acid

Guidance literature:: 4-(2-benzenesulfonylethyl)phenylamine; With sulfuric acid; sodium nitrite; In water; acetonitrile; at 4 ℃; for 1h;

ascorbic acid; In water; acetonitrile; at 4 - 20 ℃; for 17h;

Reference yield:

: 340041-90-9
4-nitrophenyl-2-(4-benzenesulfonylhydrazide)ethane

: 868618-78-4
oxo(2-{4-[2-(phenylsulfonyl)ethyl]phenyl}hydrazino)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: 5% Pd(II)/C(eggshell); hydrogen / methanol / 18 h / 60 °C / 3102.97 Torr

2.1: sulfuric acid; sodium nitrite / water; acetonitrile / 1 h / 4 °C

2.2: 4 - 20 °C

With sulfuric acid; 5% Pd(II)/C(eggshell); hydrogen; sodium nitrite; In methanol; water; acetonitrile;
DOI:10.1021/op100251q

Reference yield:

: 873-55-2
sodium benzenesulfonate

: 868618-78-4
oxo(2-{4-[2-(phenylsulfonyl)ethyl]phenyl}hydrazino)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: water; isopropyl alcohol / 42 h / 70 °C

2.1: 5% Pd(II)/C(eggshell); hydrogen / methanol / 18 h / 60 °C / 3102.97 Torr

3.1: sulfuric acid; sodium nitrite / water; acetonitrile / 1 h / 4 °C

3.2: 4 - 20 °C

With sulfuric acid; 5% Pd(II)/C(eggshell); hydrogen; sodium nitrite; In methanol; water; isopropyl alcohol; acetonitrile;
DOI:10.1021/op100251q