{2-[(3-Chloro-2-methylbenzene-1-sulfonyl)amino]-1,3-thiazol-4-yl}acetic acid

Base Information

Chemical Name:{2-[(3-Chloro-2-methylbenzene-1-sulfonyl)amino]-1,3-thiazol-4-yl}acetic acid
CAS No.:376638-09-4
Molecular Formula:C12H11 Cl N2 O4 S2
Molecular Weight:346.815
Hs Code.:
DSSTox Substance ID:DTXSID10437823
Wikidata:Q82253389

Synonyms:376638-09-4;SCHEMBL3612714;DTXSID10437823;4-Thiazoleaceticacid, 2-[[(3-chloro-2-methylphenyl)sulfonyl]amino]-;{2-[(3-Chloro-2-methylbenzene-1-sulfonyl)amino]-1,3-thiazol-4-yl}acetic acid;4-Thiazoleaceticacid,2-[[(3-chloro-2-methylphenyl)sulfonyl]amino]-

Suppliers and Price of {2-[(3-Chloro-2-methylbenzene-1-sulfonyl)amino]-1,3-thiazol-4-yl}acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of {2-[(3-Chloro-2-methylbenzene-1-sulfonyl)amino]-1,3-thiazol-4-yl}acetic acid

Chemical Property:

PSA：132.98000
LogP:3.68660
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:345.9848769
Heavy Atom Count:21
Complexity:482

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC=C1Cl)S(=O)(=O)NC2=NC(=CS2)CC(=O)O

Technology Process of {2-[(3-Chloro-2-methylbenzene-1-sulfonyl)amino]-1,3-thiazol-4-yl}acetic acid

There total 3 articles about {2-[(3-Chloro-2-methylbenzene-1-sulfonyl)amino]-1,3-thiazol-4-yl}acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 375844-31-8
ethyl 2-(2-{[(3-chloro-2-methylphenyl)sulfonyl]amino}-1,3-thiazol-4-yl)acetate

: 376638-09-4
[2-(3-chloro-2-methyl-benzenesulfonylamino)-thiazol-4-yl]-acetic acid

Guidance literature:: With potassium hydroxide; In ethanol; water; for 3h;
DOI:10.1021/jm025530f

Reference yield:

: 80563-86-6
3-chloro-2-methylbenzenesulfonyl chloride

: 376638-09-4
[2-(3-chloro-2-methyl-benzenesulfonylamino)-thiazol-4-yl]-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / pyridine / 18 h / 20 °C

2: 89 percent / KOH / ethanol; H₂O / 3 h

With pyridine; potassium hydroxide; In ethanol; water;
DOI:10.1021/jm025530f

Reference yield:

: 53266-94-7
ethyl 2-amino-1,3-thiazol-4-acetate

: 376638-09-4
[2-(3-chloro-2-methyl-benzenesulfonylamino)-thiazol-4-yl]-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / pyridine / 18 h / 20 °C

2: 89 percent / KOH / ethanol; H₂O / 3 h

With pyridine; potassium hydroxide; In ethanol; water;
DOI:10.1021/jm025530f